Tyk2 [p Tyr1055, p Tyr1054] Antibody - BSA Free

Novus Biologicals | Catalog # NBP3-16896

Novus Biologicals
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Key Product Details

Validated by

Biological Validation

Species Reactivity

Mouse, Rat

Applications

Western Blot, ELISA

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all Tyk2 Primary Antibodies »

Product Specifications

Immunogen

A synthetic phosphorylated peptide around Y1054 & Y1055 of human Tyk2 (NP_003322.3). HEYYRV

Modification

p Tyr1055, p Tyr1054

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

134 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

Novus Biologicals Rabbit Tyk2 [p Tyr1055, p Tyr1054] Antibody - BSA Free (NBP3-16896) is a polyclonal antibody validated for use in WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for Tyk2 [p Tyr1055, p Tyr1054] Antibody - BSA Free

Western Blot: Tyk2 [p Tyr1055, p Tyr1054] AntibodyBSA Free [NBP3-16896]

Western Blot: Tyk2 [p Tyr1055, p Tyr1054] AntibodyBSA Free [NBP3-16896]

Western Blot: Tyk2 [p Tyr1055, p Tyr1054] Antibody [NBP3-16896] - Western blot analysis of extracts of NIH/3T3 cells, using Tyk2 Rabbit pAb (NBP3-16896) at 1:1000 dilution.NIH/3T3 cells were treated by IFN-alpha (100 ng/ml) at 37C for 30 minutes after serum-starvation overnight. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% BSA. Detection: ECL Enhanced Kit. Exposure time: 180s.

Applications for Tyk2 [p Tyr1055, p Tyr1054] Antibody - BSA Free

Application
Recommended Usage

Western Blot

1:500 - 1:1000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.3), 50% glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Tyk2

Novel non-receptor tyrosine-protein kinase, Tyk2, belongs to the tyrosine protein kinase family and plays a role in intracellular signal transduction by being involved in the initiation of type I IFN signaling. Tyk2 is believed to phosphorylate the interferon-alpha/beta receptor alpha chain (1). It has been shown that Tyk2 links the interferon alpha/beta receptor to the cytoplasmic transcription factor that mediates activation of interferon-responsive genes (2).

Long Name

Protein tyrosine kinase 2

Alternate Names

EC 2.7.10, EC 2.7.10.2, JTK1, non-receptor tyrosine-protein kinase TYK2, tyrosine kinase 2

Gene Symbol

TYK2

Additional Tyk2 Products

Product Documents for Tyk2 [p Tyr1055, p Tyr1054] Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for Tyk2 [p Tyr1055, p Tyr1054] Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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