UBN1 Antibody

Novus Biologicals | Catalog # NBP2-26142

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (100%), Canine (100%), Mouse (100%), Porcine (100%), Rat (100%), Zebrafish (100%). Backed by our 100% Guarantee.

Applications

Western Blot, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
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Product Specifications

Immunogen

Peptide with sequence C-DNSEAYDELVPASLT corresponding to internal region according to NP_058632.2.

Specificity

Reported variants represent identical protein: NP_058632.2, NP_001072982.1.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for UBN1 Antibody

Western Blot: UBN1 Antibody [NBP2-26142]

Western Blot: UBN1 Antibody [NBP2-26142]

Western Blot: UBN1 Antibody [NBP2-26142] - (1ug/ml) staining of MOLT4 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for UBN1 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:128000

Western Blot

1 - 3 ug/ml
Application Notes
WB: Approx. 120 kDa band observed in MOLT4 lysates (calculated MW of 122 kDa band according to NP_058632.2). An additional band of unknown identity was also consistently observed at 28 kDa. This band was successfully blocked by incubation with the immunizing peptide.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: UBN1

UBN1 acts as a novel regulator of senescence. Involved in the formation of senescence-associated heterochromatin foci (SAHF), which represses expression of proliferation-promoting genes. Binds to proliferation-promoting genes. May be required for replication-i

Alternate Names

HIRA-binding protein, ubinuclein 1, ubinuclein-1, VT, VT4

Entrez Gene IDs

29855 (Human); 170644 (Mouse); 302935 (Rat)

Gene Symbol

UBN1

Additional UBN1 Products

Product Documents for UBN1 Antibody

Certificate of Analysis

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Product Specific Notices for UBN1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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