Universal Type I IFN Protein 11200-1: R&D Systems

Universal Type I IFN Protein

(Recombinant Human IFN-alpha A/D [BglII]).
(15 citations)   
11200-1
 
Stability & Storage: Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: IFN-alpha
Interferon-alpha (IFN-alpha), also known as leukocyte interferon, represents a group of related but distinct proteins that share over 95% amino acid sequence homology. They are members of the type I interferon family which share a common cell surface receptor composed of two subunits, a 100 kDa ligand-binding subunit (IFN-alpha R2) and a 125 kDa ligand binding and signal transduction subunit (IFN-alpha R1) that is involved both in ligand binding and signal transduction. IFN-alpha has both anti-viral and immunomodulatory activities on target cells.
  • Long Name:
    Interferon alpha
  • Entrez Gene IDs:
    3440 (Human)
  • Alternate Names:
    IFNalpha; IFN-alpha
Related Research Areas
Citations:

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

15 Citations: Showing 1 - 10
Filter your results:

Species
Applications
Sample Type
  1. Type I IFN counters or promotes Coxiella burnetii replication dependent on tissue
    Authors: JF Hedges, A Robison, E Kimmel, K Christense, E Lucas, A Ramstead, MA Jutila
    Infect Immun, 2016;0(0):.
    Species: Mouse
    Sample Type: In Vivo
    Application: In Vivo
  2. Carcinoma-astrocyte gap junctions promote brain metastasis by cGAMP transfer
    Nature, 2016;533(7604):493-8.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  3. ATF3 Is a Key Regulator of Macrophage IFN Responses.
    Authors: Labzin L, Schmidt S, Masters S, Beyer M, Krebs W, Klee K, Stahl R, Lutjohann D, Schultze J, Latz E, De Nardo D
    J Immunol, 2015;195(9):4446-55.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  4. Annexin V incorporated into influenza virus particles inhibits gamma interferon signaling and promotes viral replication.
    Authors: Berri F, Haffar G, Le V, Sadewasser A, Paki K, Lina B, Wolff T, Riteau B
    J Virol, 2014;88(19):11215-28.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  5. SECTM1 produced by tumor cells attracts human monocytes via CD7-mediated activation of the PI3K pathway.
    Authors: Wang T, Ge Y, Xiao M, Lopez-Coral A, Li L, Roesch A, Huang C, Alexander P, Vogt T, Xu X, Hwang W, Lieu M, Belser E, Liu R, Somasundaram R, Herlyn M, Kaufman R
    J Invest Dermatol, 2014;134(4):1108-18.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  6. RIG-I modulates Src-mediated AKT activation to restrain leukemic stemness.
    Authors: Li X, Jiang L, Chen L, Ding M, Guo H, Zhang W, Zhang H, Ma X, Liu X, Xi X, Chen S, Chen Z, Zhu J
    Mol Cell, 2014;53(3):407-19.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  7. An innate immunity-regulating virulence determinant is uniquely encoded by the Andes virus nucleocapsid protein.
    Authors: Cimica V, Dalrymple N, Roth E, Nasonov A, Mackow E
    MBio, 2014;5(1):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  8. BST-2/tetherin-mediated restriction of chikungunya (CHIKV) VLP budding is counteracted by CHIKV non-structural protein 1 (nsP1).
    Authors: Jones P, Maric M, Madison M, Maury W, Roller R, Okeoma C
    Virology, 2013;438(1):37-49.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  9. Evasion of superinfection exclusion and elimination of primary viral RNA by an adapted strain of hepatitis C virus.
    Authors: Webster, Brian, Ott, Melanie, Greene, Warner C
    J Virol, 2013;87(24):13354-69.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  10. Cetuximab-activated natural killer and dendritic cells collaborate to trigger tumor antigen-specific T-cell immunity in head and neck cancer patients.
    Authors: Srivastava R, Lee S, Andrade Filho P, Lord C, Jie H, Davidson H, Lopez-Albaitero A, Gibson S, Gooding W, Ferrone S, Ferris R
    Clin Cancer Res, 2013;19(7):1858-72.
    Species: Human
    Sample Type:
  11. Regulation of development of CD56 bright CD11c + NK-like cells with helper function by IL-18.
    Authors: Li W, Okuda A, Yamamoto H, Yamanishi K, Terada N, Yamanishi H, Tanaka Y, Okamura H
    PLoS ONE, 2013;8(12):e82586.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  12. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors.
    Authors: Wilson TR, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, Peng J, Lin E, Wang Y, Sosman J, Ribas A, Li J, Moffat J, Sutherlin DP, Koeppen H, Merchant M, Neve R, Settleman J
    Nature, 2012;487(7408):505-9.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  13. Molecular signatures associated with Mx1-mediated resistance to highly pathogenic influenza virus infection: mechanisms of survival.
    Authors: Cilloniz C, Pantin-Jackwood MJ, Ni C, Carter VS, Korth MJ, Swayne DE, Tumpey TM, Katze MG
    J. Virol., 2012;86(5):2437-46.
    Species: Mouse
    Sample Type: In Vivo
    Application: In Vivo
  14. Human cytomegalovirus IE1 protein elicits a type II interferon-like host cell response that depends on activated STAT1 but not interferon-gamma.
    Authors: Knoblach T, Grandel B, Seiler J, Nevels M, Paulus C
    PLoS Pathog., 2011;7(4):e1002016.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  15. Chemerin expression marks early psoriatic skin lesions and correlates with plasmacytoid dendritic cell recruitment.
    Authors: Albanesi C, Scarponi C, Pallotta S, Daniele R, Bosisio D, Madonna S, Fortugno P, Gonzalvo-Feo S, Franssen JD, Parmentier M, De Pita O, Girolomoni G, Sozzani S
    J. Exp. Med., 2009;206(1):249-58.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
Expand to show all 15 Citations

Have you used Universal Type I IFN Protein?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Order Details

Calculators

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷
R&D Systems Guarantee

Feedback

Customer Information