VEGFR1/Flt-1 Antibody

Name: VEGFR1/Flt-1 Antibody
Brand: Novus Biologicals
SKU: NB100-685
Price: 669 USD
Availability: InStock

Novus Biologicals | Catalog # NB100-685

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Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

View all VEGFR1/Flt-1 Primary Antibodies »

Product Specifications

Immunogen

Synthetic peptide: C-AELERKIACCSPPPDYN, corresponding to amino acids 1312-1328 of human VEGF Receptor 1 (C-terminus).

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Mouse, Rat.

Localization

Cytoplasmic

Marker

Endothelial Cell Marker

Specificity

This reacts with a 180 kD protein, known as VEGFR1/Flt-1 or vascular endothelial growth factor receptor 1. VEGFR1/Flt-1 is a cell membrane receptor kinase. VEGFR1/Flt-1 has a high affinity receptor for vascular endothelial growth factor and is putatively involved in the growth of endothelial cells and angiogenesis.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for VEGFR1/Flt-1 Antibody

Immunohistochemistry-Paraffin: VEGFR1/Flt-1 Antibody [NB100-685]

Immunohistochemistry-Paraffin: VEGFR1/Flt-1 Antibody [NB100-685] - Formalin fixed paraffin embedded human placenta stained with VEGFR1/Flt-1 antibody (NB100-685).

Immunohistochemistry: VEGFR1/Flt-1 Antibody [NB100-685]

Immunohistochemistry: VEGF R1/Flt-1 Antibody [NB100-685] - Formalin fixed paraffin embedded human angiosarcoma stained with Flt-1.

Applications for VEGFR1/Flt-1 Antibody

Application

Recommended Usage

Immunohistochemistry

1:25-1:50

Immunohistochemistry-Frozen

1:50-1:100

Immunohistochemistry-Paraffin

1:25-1:50

Application Notes

IHC-P: recommended pretreatment of citrate buffer, pH 6.0. Recommended incubation time of 30 min at RT.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.4), 0.2% BSA, Tween-20

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: VEGFR1/Flt-1

The receptor for VEGF, VEGFB and PGF has tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. Isoform SFlt1 may have an inhibitory role in angiogenesis. VEGFR 1 is a cell membrane receptor kinase. It has a high affinity receptor for vascular endothelial growth factor and is putatively involved in the growth of endothelial cells and angiogenesis.

Long Name

Vascular Endothelial Growth Factor Receptor 1

Alternate Names

Flt-1, FLT1, FRT, VEGF R1, VEGFR-1

Entrez Gene IDs

2321 (Human); 14254 (Mouse); 54251 (Rat)

Gene Symbol

FLT1

UniProt

P17948

Additional VEGFR1/Flt-1 Products

Product Documents for VEGFR1/Flt-1 Antibody

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Certificate of Analysis

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Product Specific Notices for VEGFR1/Flt-1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.