VKORC1 Antibody

Novus Biologicals | Catalog # NBP3-12232

Novus Biologicals
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, ELISA, Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit
View all VKORC1 Primary Antibodies »

Product Specifications

Immunogen

Synthetic peptide taken within amino acid region 10-60 on human VKORC1 protein.

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for VKORC1 Antibody

Western Blot: VKORC1 Antibody [NBP3-12232]

Western Blot: VKORC1 Antibody [NBP3-12232]

Western Blot: VKORC1 Antibody [NBP3-12232] - WB. 1:500 antibody dilution in DiluObuffer. Apparent MW is 20 kDa.
Immunohistochemistry-Paraffin: VKORC1 Antibody [NBP3-12232]

Immunohistochemistry-Paraffin: VKORC1 Antibody [NBP3-12232]

Immunohistochemistry-Paraffin: VKORC1 Antibody [NBP3-12232] - 1:100 dilution in IHC blocking buffer. DAB (brown) staining and Hematoxylin QS (blue) counterstain. 40X magnification on Leica DM4000. FFPE section.
Immunohistochemistry-Paraffin: VKORC1 Antibody [NBP3-12232]

Immunohistochemistry-Paraffin: VKORC1 Antibody [NBP3-12232]

Immunohistochemistry-Paraffin: VKORC1 Antibody [NBP3-12232] - 1:100 dilution in IHC blocking buffer. DAB (brown) staining and Hematoxylin QS (blue) counter stain. 40X magnification.

Applications for VKORC1 Antibody

Application
Recommended Usage

ELISA

1:50000

Immunohistochemistry

1:250

Immunoprecipitation

1:200

Western Blot

1:500

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

Contains Tris, HCl/glycine buffer (pH 7.4-7.8), 30% glycerol, 0.5% BSA, along with cryo-protective agents, and HEPES (exact storage and stabilization buffer information is proprietary).

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Store at -20C long term. Avoid freeze-thaw cycles.

Background: VKORC1

Vitamin K is essential for blood clotting but must be enzymatically activated. This enzymatically activated form of vitamin K is a reduced form required for the carboxylation of glutamic acid residues in some blood-clotting proteins. The product of this gene encodes the enzyme that is responsible for reducing vitamin K 2,3-epoxide to the enzymatically activated form. Fatal bleeding can be caused by vitamin K deficiency and by the vitamin K antagonist warfarin, and it is the product of this gene that is sensitive to warfarin. In humans, mutations in this gene can be associated with deficiencies in vitamin-K-dependent clotting factors and, in humans and rats, with warfarin resistance. Two pseudogenes have been identified on chromosome 1 and the X chromosome. Two alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq]

Alternate Names

EC 1.1.4.1, EDTP308, FLJ00289, IMAGE3455200, MST576, phylloquinone epoxide reductase, vitamin K dependent clMST134, vitamin K epoxide reductase complex subunit 1, vitamin K epoxide reductase complex, subunit 1, Vitamin K1 2,3-epoxide reductase subunit 1, vitamin K1 epoxide reductase (warfarin-sensitive), VKCFD2, VKORMGC2694

Gene Symbol

VKORC1

Additional VKORC1 Products

Product Documents for VKORC1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for VKORC1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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