VPC 23019

  ( 3 citations )    
Product Datasheet
Catalog Number:4195
Chemical Name:2-Amino-N-(3-octylphenyl)-3-(phosphonooxy)-propanamaide
Product Details
Citations (3)
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Reviews
Biological Activity
Sphingosine-1-phosphate receptor antagonist; inhibits S1P1 and S1P3 receptors (pKi values are 7.86 and 5.93 respectively).
Technical Data
  • M.Wt:
    372.4
  • Formula:
    C17H29N2O5P
  • Solubility:
    Soluble to 10 mM in Acidified DMSO (5% 1N HCl in DMSO) with gentle warming and to 50 mM in 2eq. NaO
  • Purity:
    >95
  • Storage:
    Store at -20°C
  • CAS No:
    449173-19-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for VPC 23019 include:

3 Citations: Showing 1 - 3
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  1. Sphingosine-1-phosphate receptor inhibition prevents denervation-induced dendritic atrophy.
    Authors: Willems Et al.
    Evid Based Complement Alternat Med  2016;4:28
  2. Sphingosylphosphorylcholine inhibits macrophage adhesion to vascular smooth muscle cells
    Authors: Wirrig Et al.
    Biochemical Pharmacology  2016;115:43
  3. Sphingosine kinases and sphingosine-1-phosphate are critical for transforming growth factor beta-induced extracellular signal-regulated kinase 1 and 2 activation and promotion of migration and invasion of esophageal cancer cells.
    Authors: Miller Et al.
    Mol Cell Biol  2008;28:4142

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