Chemical Name: 3-Fluoro-5-[3-(2-pyridinyl)-1,2,4-oxadiazol-5-yl]-benzonitrile
Biological ActivityNegative allosteric modulator of mGlu 5 receptors. Displays high affinity for the MPEP (Cat. No. 1212) binding site; acts as a full antagonist and blocks the glutamate response to mGlu 5 (IC 50 = 24.4 nM). Selective for mGlu 5 over mGlu 1 mGlu 3 and mGlu 4. Exhibits anxiolytic activity in rodent models of anxiety. Analog available (Cat. No. 4323).
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
No product specific FAQs exist for this product, however you mayView all Small Molecule FAQs
VersaClone cDNA Plasmids
Reviews for VU 0285683
There are currently no reviews for this product. Be the first to review VU 0285683 and earn rewards!
Have you used VU 0285683?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image