ZDHHC8 Antibody

Novus Biologicals | Catalog # NB100-57849

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Canine (100%), Mouse (100%), Porcine (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Western Blot, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
View all ZDHHC8 Primary Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-QRDHPQLKTPPSK corresponding to internal region according to NP_037505.1.

Epitope

QRDHPQLKTPPSK

Specificity

This antibody is expected to recognise isoform 2 (NP_037505.1) only.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for ZDHHC8 Antibody

Western Blot: ZDHHC8 Antibody [NB100-57849]

Western Blot: ZDHHC8 Antibody [NB100-57849]

Western Blot: ZDHHC8 Antibody [NB100-57849] - (0.1ug/ml) staining of Human Brain (Frontal Cortex) lysate (35ug protein in RIPA buffer) with (B) and without (A) blocking with the immunising peptide. Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for ZDHHC8 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:16000

Western Blot

1 - 3 ug/ml
Application Notes
WB: Approx. 80-85 kDa band observed in human brain (frontal cortex) lysates (calculated MW of 81.4 kDa band according to NP_037505.1). An additional band of 48 kDa band was consistently observed, however this band was not blocked by the immunizing peptide and it is therefore a non-specific signal. We call for caution when used for other assays than WB.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: ZDHHC8

The gene ZDHHC8, which encodes a putative palmitoyltransferase at 22q11, has been proposed as a gene which may increase liability to schizophrenia. Chromosome region 22q11 has been proposed as a major candidate locus for genes leading to susceptibility to schizophrenia.

Alternate Names

DHHC8, EC 2.3.1, EC 2.3.1.-, KIAA1292DHHC-8, membrane-associated DHHC8 zinc finger protein, probable palmitoyltransferase ZDHHC8, ZDHHCL1, Zinc finger DHHC domain-containing protein 8, Zinc finger protein 378, zinc finger, DHHC-type containing 8, ZNF378zinc finger, DHHC domain like containing 1

Entrez Gene IDs

29801 (Human); 27801 (Mouse); 303796 (Rat)

Gene Symbol

ZDHHC8

UniProt

Q9ULC8 (Human)

Additional ZDHHC8 Products

Product Documents for ZDHHC8 Antibody

Certificate of Analysis

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Product Specific Notices for ZDHHC8 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for ZDHHC8 Antibody

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