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7 results for "ErbB4/Her4 Small Molecules and Peptides" in Products
ErbB4/Her4 Small Molecules and Peptides
ErbB4, also known as Her4, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors. ErbB family members serve as receptors for the EGF family of growth factors. ErbB4 ligands include the neuregulins, betacellulin and heparin-binding EGF-like growth factor (HB-EGF).
EGFR-kinase inhibitor. Also JAK2, JAK3 inhibitor
| Alternate Names: | Tyrphostin AG 490 |
| Chemical Name: | (E)-2-Cyano-3-(3,4-dihydrophenyl)-N-(phenylmethyl)-2-propenamide |
| Purity: | ≥98% |
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Potent irreversible pan ErbB inhibitor
| Alternate Names: | PF00299804 |
| Chemical Name: | (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-4-(1-piperidinyl)-2-butenamide |
| Purity: | ≥98% |
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Negative control for PP 2 (Cat. No. 1407)
| Chemical Name: | 1-Phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| Purity: | ≥98% |
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Potent ErbB receptor family inhibitor
| Chemical Name: | N4-(3-Bromophenyl)-N6-methyl-pyrido[3,4-d]pyrimidine-4,6-diamine |
| Purity: | ≥98% |
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Potent EGFR and VEGFR inhibitor
| Chemical Name: | 6-[4-[(4-Ethyl-1-piperazinyl)methyl]phenyl]-N-[(1R)-1-phenylethyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine |
| Purity: | ≥98% |
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Potent dual specificity EGFR/HER2 inhibitor; active in vivo
| Alternate Names: | BIBW2992 |
| Chemical Name: | (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide dimaleate |
| Purity: | ≥98% |
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Potent EGFR PROTAC® Degrader
| Alternate Names: | Iressa-based PROTAC 3 |
| Chemical Name: | (2S,4R)-1-((S)-2-(3-(2-((5-((4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)pentyl)oxy)ethoxy)propanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide |
| Purity: | ≥98% |
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