5 results for "Adenosine A2b R" in Products
Adenosine A2b R Products
The Adenosine A2b Receptor (ADORA2B) gene codes for a receptor located on chromosome 17 (near the Smith-Magenis syndrome region) that initiates adenylyl cyclase in the presence of adenosine. The encoded adenoside receptor is 332 amino acids long, around 36 kDA, and is member to the G protein-coupled receptor superfamily and interacts with netrin-1 to promote axon elongation. ADORA2B has been associated with cholera, hepatitis B, breast cancer, carcinoma, eclampsia, ischemia, asthma, cystic fibrosis, astrocytoma, and atherosclerosis. It is involved in signal transduction IP3 signaling, GPCR ligand binding and signaling, and the methotrexate pathway through interactions with the EZR, NTN1, ADA, DDC, and SLC9A3R2 genes.
High affinity adenosine agonist
| Alternate Names: | 5'-N-Ethylcarboxamidoadenosine |
| Chemical Name: | 1-(6-Amino-9H-purin-9-yl)-1-deoxy-N-ethyl-β-D-ribofuranuronamide |
| Purity: | ≥98% |
Endogenous adenosine receptor agonist
| Chemical Name: | 9-β-D-Ribofuranosyl-9H-purin-6-amine |
| Purity: | ≥98% |
Potent partial A2B agonist; cardioprotective
| Chemical Name: | 2-[[6-Amino-3,5-dicyano-4-[4-(cyclopropylmethoxy)phenyl]-2-pyridinyl]thio]-acetamide |
| Purity: | ≥98% |
Adenosine receptor agonist
| Alternate Names: | 2-CADO |
| Chemical Name: | 6-Amino-2-chloropurine riboside |
| Purity: | ≥98% |
Potent adenosine A2A and A2B receptor partial agonist
| Chemical Name: | 2-Amino-4-(4-hydroxyphenyl)-6-[(1H-imidazol-2-ylmethyl)thio]-3,5-pyridinecarbonitrile |
| Purity: | ≥98% |
