4 results for "Aurora Kinase Inhibitors" in Products

Aurora Kinase Inhibitors

Aurora kinases are a family of three highly homologous serine/threonine kinases that play a critical role in regulating many of the processes that are pivotal to mitosis. Each isoform, Aurora A, Aurora B and Aurora C, has a different function in the control of this process.

Aurora A is involved in regulating many of the early mitotic events where its levels peak, particularly during the G2 phase. One target of Aurora A is cdc25b, a direct regulator of the cyclin B1-Cdk1 complex, which provides ...

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Inhibits Aurora kinase B

Chemical Name: N-[4-[[6-Methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinazolinyl]amino]phenyl]benzamide
Purity: ≥98%
Inhibits Aurora kinase B
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Potent Aurora kinase B inhibitor

Chemical Name: N-[2,3-Dihydro-2-oxo-3-[(3Z)-phenyl[[4-(1-piperidinylmethyl)phenyl]amino]methylene]-1H-indol-5-yl]-ethanesulfonamide hydrochloride
Purity: ≥98%
Potent Aurora kinase B inhibitor
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Potent, selective Aurora kinase A inhibitor

Chemical Name: 2-[(5-Hydroxy-1,5-dimethylhexyl)amino]-4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)amino]-3-pyridinecarbonitrile hydrochloride
Purity: ≥98%
Potent, selective Aurora kinase A inhibitor
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Potent pan-Aurora kinase inhibitor

Chemical Name: N-[4-[[3-(2-Amino-4-pyrimidinyl)-2-pyridinyl]oxy]phenyl]-4-(4-methyl-2-thienyl)-1-phthalazinamine
Purity: ≥98%
Potent and selective pan-Aurora kinases inhibitor
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