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4 results for "Class III Histone Deacetylases Inhibitors Small Molecules and Peptides" in Products
Class III Histone Deacetylases Inhibitors Small Molecules and Peptides
Sirtuins (also known as Silent information regulator (Sir2)-like family deacetylase) are a family of histone deacetylase enzymes. Sirtuins are classified as class III HDACs. These enzymes can be found in the cytoplasm, mitochondria or nucleus of the cell and are ubiquitously expressed. Sirtuins catalyze the removal of acetyl groups from lysine residues in histones and non-histone proteins, which is coupled to NAD+ hydrolysis.
In general, sirtuins do not act autonomously but as components of ...
Selective SIRT1 inhibitor
| Chemical Name: | 6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide |
| Purity: | ≥98% |
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Selective SIRT2 inhibitor; brain penetrant
| Chemical Name: | N-(3-Bromophenyl)-3-[(hexahydro-1H-azepin-1-yl)sulfonyl]benzamide |
| Purity: | ≥98% |
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Selective inhibitor of SIRT2
| Chemical Name: | 2-[(4,6-Dimethyl-2-pyrimidinyl)thio]-N-[5-(1-naphthalenylmethyl)-2-thiazolyl]acetamide |
| Purity: | ≥98% |
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Nicotinamide synthesized to Ancillary Material Grade
| Chemical Name: | Pyridine-3-carboxamide |
| Purity: | ≥99% |
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