7 results for "DYRK1A Small Molecules and Peptides" in Products
DYRK1A Small Molecules and Peptides
DYRK1A encodes a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. This gene is a homolog ...
DYRK1A/B inhibitor
| Chemical Name: | (1Z)-1-(3-Ethyl-5-hydroxy-2(3H)-benzothiazolylidene)-2-propanone |
| Purity: | ≥98% |
Potent and selective DYRK1A inhibitor
| Chemical Name: | 7-Methoxy-1-methyl-9H-pyrido[3,4-b]indole |
| Purity: | ≥98% |
Potent and selective DYRK1A/B inhibitor
| Alternate Names: | R05454948 |
| Chemical Name: | N-[2-Chloro-5-[[[(3-chlorophenyl)methyl]amino]carbonyl]phenyl]-7,8-dihydro-2-methoxy-7-oxopyrido[2,3-d]pyrimidine-6-carboxamide |
| Purity: | ≥98% |
Potent and selective pan-CLK inhibitor; also inhibits DYRK1A/B
| Chemical Name: | 4-[1,1-Dimethyl-2-(4-methyl-1-piperazinyl)-2-oxoethyl]-N-[6-(4-pyridinyl)imidazo[1,2-a]pyridin-2-yl]benzamide |
| Purity: | ≥98% |
Inhibitor of Clk and DYRK kinases
| Chemical Name: | 5-(1,3-Benzodioxol-5-yl)-N-[(3,5-dichlorophenyl)methyl]-4-pyrimidinamine hydrochloride |
| Purity: | ≥98% |
Potent and selective DYRK inhibitor; orally bioavailable.
| Chemical Name: | (5Z)-2-[(2,6-Dichlorophenyl)amino]-5-(6-quinoxalinylmethylene)-4(5H)-thiazolone |
| Purity: | ≥95% |
Potent LMTK3 inhibitor
| Chemical Name: | 6-(Pyridin-4-yl)-3-(3-(trifluoromethoxy)phenyl)imidazo[1,2-b]pyridazine |
| Purity: | ≥98% |
