5 results for "ErbB3/Her3 Proteome Profiler Antibody Arrays" in Products

ErbB3/Her3 Proteome Profiler Antibody Arrays

ErbB3, also called Her3 (human epidermal growth factor receptor 3) in humans, is a type I transmembrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors. ErbB3 binds neuregulins NRG1 and NRG2, but lacks a working kinase domain; heterodimerization with another ErbB receptor is required for signaling. ErbB3 is important in development of Schwann cells, neural crest cells, heart valves and the sympathetic nervous system. When expressed with ErbB2 in breast, skin, ovary and gastrointestinal tumors, ErbB3 is a potent mitogen.

Contains 4 membranes - each spotted in duplicate with 49 different RTK antibodies

Reactivity: Human
Applications:
Detection of Human Receptor Tyrosine Kinase Phosphorylation in KATO-III Cell Line.
(2)
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Contains 4 membranes - each spotted in duplicate with 39 different RTK antibodies

Reactivity: Mouse
Applications:
The Mouse Phospho-RTK Array detects multiple tyrosine phosphorylated receptors in untreated and ligand-treated cell lysates.
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Contains 4 membranes-each spotted in duplicate with 84 different cancer-related antibodies

Reactivity: Human
Applications:
R&D Systems Proteome Profiler Antibody Array Kits
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Contains 4 membranes - 2 spotted in duplicate with 62 different non-hematopoietic antibodies and 2 spotted in duplicate with 57 common antibodies

Reactivity: Human
Applications:
R&D Systems Proteome Profiler Antibody Array Kits
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Contains 4 membranes-each spotted in duplicate with 49 different antibodies to ubiquitin target proteins

Reactivity: Human
Applications:
R&D Systems Proteome Profiler Antibody Array Kits
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