4 results for "Glucocorticoid Receptor Compounds Small Molecules and Peptides" in Products
Glucocorticoid Receptor Compounds Small Molecules and Peptides
Glucocorticoid Receptor (GR), also known as NR3C1, is a member of the NR3 family of nuclear receptors. It mediates the physiological and pharmacological actions of glucocorticoids, including modulation of immune responses, mediation of stressor-induced adaptations, and regulation of metabolism. GR is composed of a N-terminal transactivation domain (NTD, amino acids [aa] 1-421), a central DNA-binding domain (DBD, aa 422-486), and a C-terminal ligand-binding domain (LBD, aa 528-777). A flexible ...
Anti-inflammatory glucocorticoid
| Chemical Name: | (11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methyl-pregna-1,4-diene-3,20-dione |
| Purity: | ≥98% |
Adrenal glucocorticoid; immunosuppressant
| Chemical Name: | 11β,17α,21-Trihydroxypregn-4-ene-3,20-dione |
| Purity: | ≥98% |
Dexamethasone synthesized to Ancillary Material Grade
| Chemical Name: | (11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione |
| Purity: | ≥98% |
Synthetic glucocorticoid; anti-inflammatory and chemopreventive
| Chemical Name: | (11β,16α)-16,17-[Butylidenebis(oxy)]-11,21-dihydroxypregna-1,4-diene-3,20-dione |
| Purity: | ≥98% |