5 results for "Histamine H4R" in Products

Histamine H4R Products

Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by a family of histamine receptors, which are a subset of the G protein-coupled receptor superfamily. Histamine H4R is a histamine receptor that is predominantly expressed in hematopoietic cells. Histamine H4R is thought to play a role in inflammation and allergy reponses.

H3 antagonist; also H4 inverse agonist

Chemical Name: N-Cyclohexyl-4-(imidazol-4-yl)-1-piperidinecarbothioamide
Purity: ≥98%
H3 antagonist; also H4 inverse agonist
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Selective H4 antagonist

Chemical Name: 1-[(5-Chloro-1H-indol-2-yl)carbonyl]-4-methylpiperazine
Purity: ≥98%
Selective H4 antagonist
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Selective H4 antagonist; orally active

Alternate Names: VUF 6002
Chemical Name: 1-[(5-Chloro-1H-benzimidazol-2-yl)carbonyl]-4-methylpiperazine maleate
Purity: ≥98%
Selective H4 antagonist; orally active
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Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent

Chemical Name: (3aR*,12bR*)-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole maleate
Purity: ≥98%
Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent
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High affinity and selective histamine H4 antagonist; orally bioavailable

Chemical Name: 4-[(3R)-3-Amino-1-pyrrolidinyl]-6-(1-methylethyl)-2-pyridinamine dihydrochloride
Purity: ≥98%
High affinity and selective histamine H4 antagonist; orally bioavailable
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