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4 results for "KCC2/SLC12A5 Small Molecules and Peptides" in Products
KCC2/SLC12A5 Small Molecules and Peptides
SLC12A5 is an integral membrane K-Cl cotransporter that can function in either a net efflux or influx pathway, depending on the chemical concentration gradients of potassium and chloride. It can act as a homomultimer, or as a heteromultimer with other K-Cl cotransporters, to maintain chloride homeostasis in neurons. Alternative splicing of this gen...
Potent and selective KCC2 inhibitor
| Chemical Name: | N-Cyclopropyl-N-(4-methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]acetamide |
| Purity: | ≥98% |
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Selective KCC2 activator
| Chemical Name: | (5Z)-5-[(4-Fluoro-2-hydroxyphenyl)methylene]-2-(tetrahydro-1-(2H)-pyridazinyl)-4(5H)-thiazolone |
| Purity: | ≥98% |
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K+/Cl- cotransporter 2 (KCC2) activator; orally bioavailable prodrug of CLP 257 (Cat. No.5242)
| Chemical Name: | (Z)-5-Fluoro-2-((4-oxo-2-(tetrahydropyridazin-1(2H)-yl)thiazol-5(4H)-ylidene)methyl)phenyl pyrrolidine-1-carboxylate |
| Purity: | ≥98% |
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Na+/2Cl-/K+ (NKCC) symporter inhibitor
| Chemical Name: | 3-(Aminosulfonyl)-5-(butylamino)-4-phenoxybenzoic acid |
| Purity: | ≥98% |
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