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Potent and highly selective KCa3.1 (IK) channel blocker
Selective negative modulator of KCa2 (SK) channels; inhibits SK currents
Activates Cl- conductance and hKCa3.1 channels
KCa3.1 (IK) and KCa2 (SK) channel activator
Positive modulator of KCa2 (SK) and KCa3.1 (IK) channels
Cytochrome P450 inhibitor; antifungal
Potent negative modulator of KCa2.3 and KCa3.1 channels