NS 309

  ( 4 citations )    
Product Datasheet
Catalog Number:3895
Chemical Name:6,7-Dichloro-1H-indole-2,3-dione 3-oxime
Product Details
Citations (4)
Reviews
Biological Activity
Positive modulator of small- and intermediate- conductance Ca2+-activated K+ channels (KCa2 and KCa3.1 channels); increases Ca2+ sensitivity. Displays no activity at BK channels.
Technical Data
  • M.Wt:
    231.04
  • Formula:
    C8H4Cl2N2O2
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >98
  • Storage:
    Store at +4°C
  • CAS No:
    18711-16-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for NS 309 include:

4 Citations: Showing 1 - 4
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  1. Molecular overlap in the regulation of SK channels by small molecules and phosphoinositides.
    Authors: Zhang Et al.
    Neurochem Int  2015;1:e1500008
  2. In vivo activation of the SK channel in the spinal cord reduces the NMDA receptor antagonist dose needed to produce antinociception in an inflammatory pain model.
    Authors: Hipólito Et al.
    Pain  2015;156:849
  3. Sex differences in endothelial function in porcine coronary arteries: a role for H2O2 and gap junctions?.
    Authors: Wong Et al.
    Br J Pharmacol  2014;171:2751
  4. KCa3.1 channels are involved in the infiltrative behavior of glioblastoma in vivo.
    Authors: D'Alessandro Et al.
    Cell Death Dis  2013;4:e773

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