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5 results for "LRRK2 Inhibitors Small Molecules and Peptides" in Products
LRRK2 Inhibitors Small Molecules and Peptides
Leucine-rich repeat kinase 2 (LRRK2 or RIP7) is a large multidomain protein kinase that includes leucine-rich repeats and a GTPase domain. It is a member of the receptor interacting protein kinase family.
The biological function and regulation of LRRK2 is poorly understood, however, the enzyme is constitutively expressed in neurons and glial cells and is associated with certain neurodegenerative diseases. Autosomal dominant missense mutations in LRRK2 are commonly associated with late-onset ...
| Chemical Name: | rel-3-[6-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-4-pyrimidyl]-5-[(1-methylcyclopropyl)oxy]-1H-indazole |
| Purity: | ≥98% |
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| Chemical Name: | 5,11-Dihydro-2-[[2-methoxy-4-[[4-(4-methyl-1-piperazinyl)-1-piperidinyl]carbonyl]phenyl]amino]-5,11-dimethyl-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one |
| Purity: | ≥98% |
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| Chemical Name: | 5-(2-Fluoro-4-pyridinyl)-2-(phenylmethoxy)-N-3-pyridinylbenzamide |
| Purity: | ≥98% |
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| Chemical Name: | N-[2-[[5-Fluoro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]phenyl]methanesulfonamide |
| Purity: | ≥98% |
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| Chemical Name: | [4-[[5-Chloro-4-(methylamino)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino]-3-methoxyphenyl]-4-morpholinyl-methanone |
| Purity: | ≥98% |
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