5 results for "Lysine (K)-specific Demethylase 6B/KDM6B Small Molecules and Peptides" in Products
Lysine (K)-specific Demethylase 6B/KDM6B Small Molecules and Peptides
JMJD3 is a histone demethylase that specifically demethylates trimethylated and dimethylated 'Lys-27' of histone H3, thereby playing a central role in histone code. JMJD3 is also important for the regulation of posterior development by regulating HOX gene expression. JMJD3 is involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation. It has also been shown to be essential to mammalian epidermal differentiation and is upregulated in prostate cancer.
JMJD3 antibodies are useful tools for epigenetics research and specifically for histone modification studies.
Histone KDM inhibitor; cell permeable
| Chemical Name: | N-[2-(2-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine ethyl ester |
| Purity: | ≥98% |
Potent JMJD3/UTX inhibitor
| Chemical Name: | N-[2-(2-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine |
| Purity: | ≥98% |
Pan Jumonji inhibitor; active in vivo
| Chemical Name: | 5-Chloro-2-[(E)-2-[phenyl(pyridin-2-yl)methylidene]hydrazin-1-yl]pyridine |
| Purity: | ≥98% |
Histone demethylase inhibitor; cell permeable
| Alternate Names: | 5-carboxy-8HQ |
| Chemical Name: | 8-Hydroxy-5-quinolinecarboxylic acid |
| Purity: | ≥98% |
Inactive isomer of GSK J4 (Cat. No. 4594); cell permeable
| Chemical Name: | N-[2-(3-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine ethyl ester hydrochloride |
| Purity: | ≥98% |
