4 results for "Melatonin R1A/MT1/MTNR1A Small Molecules and Peptides" in Products

Melatonin R1A/MT1/MTNR1A Small Molecules and Peptides

Melatonin Receptor 1A encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin. [provided by RefSeq]

Endogenous hormone; agonist at MT1 and MT2

Chemical Name: N-Acetyl-5-methoxytryptamine
Purity: ≥98%
Endogenous hormone; agonist at MT1 and MT2
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Competitive melatonin MT1/MT2 antagonist

Chemical Name: N-Acetyl-2-benzyltryptamine
Purity: ≥98%
Competitive melatonin MT1/MT2 antagonist
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Very high affinity and selective melatonin receptor agonist

Alternate Names: Ramelteon
Chemical Name: N-[2-[(8S)-1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-yl]ethyl]propanamide
Purity: ≥98%
Very high affinity and selective melatonin receptor agonist
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Potent melatonin agonist

Chemical Name: N-[2-(5-Methoxy-2-phenylindol-3-yl)ethyl]acetamide
Purity: ≥98%
Potent melatonin agonist
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