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5 results for "mGluR1" in Products
mGluR1 Products
Metabotropic glutamate receptor 1 (mGluR1) is a 130 kDa, 7-transmembrane glycoprotein that belongs to group I of the C-family of G-protein coupled receptors. On neurons, mGluR1 is postsynaptic, associates with Gq-like proteins, mobilizes intracellular Ca++, and influences ion channel activity. Mature mGluR1 is 1176 amino acids...
Potent and selective negative allosteric modulator of mGlu1 receptors; also mGlu1 inverse agonist
| Chemical Name: | 4-[1-(2-Fluoro-3-pyridinyl)-5-methyl-1H-1,2,3-triazol-4-yl]-3,6-dihydro-N-methyl-N-(1-methylethyl)-1(2H)-pyridinecarboxamide |
| Purity: | ≥98% |
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Potent and selective negative allosteric modulator of mGlu1 receptors
| Chemical Name: | 3-[(3R)-3-Methyl-4-(tricyclo[3.3.1.13,7]dec-1-ylcarbonyl)-1-piperazinyl]-2-pyridinecarbonitrile hydrochloride |
| Purity: | ≥98% |
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Positive allosteric modulator of mGlu1 receptors
| Chemical Name: | (2S)-2-(4-Fluorophenyl)-1-[(4-methylphenyl)sulfonyl]-pyrrolidine |
| Purity: | ≥98% |
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Positive allosteric modulator of group I mGlu receptors
| Chemical Name: | (9H-Xanthen-9-ylcarbonyl)-carbamic acid butyl ester |
| Purity: | ≥98% |
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Potent and selective negative allosteric modulator of mGlu1 receptors
| Chemical Name: | 4-Fluoro-N-[4-[6-(isopropylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl]-N-methylbenzamide |
| Purity: | ≥98% |
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