110 results for "MTH1" in Products
MTH1 Products
Oxygen radicals damage chromosomal DNA causing cell death and inducing mutations. Among the various classes of DNA damage caused by oxygen radicals, an oxidized form of guanine base (8-oxoguanine) appears to be important as it can pair with cytosine and adenine and G:C to T:A transversion mutation occurs. A significant amount of 8-OxoG is formed in the chromosomal DNA of mammalian cells, with most damaged nucleotides excised from the DNA and excreted in the urine. Along with 8-oxoG being ...
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | KO, IHC, WB, ICC/IF, Simple Western, + 2 More |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
Degrader of MTH1 fusion proteins for use within the aTAG system
| Alternate Names: | CFT 4531 |
| Chemical Name: | N-Cyclopropyl-6-(4-((4-(4-(((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)methyl)-1H-1,2,3-triazol-1-yl)butyl)carbamoyl)-3-fluorophenyl)-7-fluoro-4-(phenylamino)quinoline-3-carboxamide |
| Purity: | ≥98% |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #PSH02-40 |
| Applications: | IHC, WB, Flow |
MTH1 inhibitor
| Chemical Name: | 3-[(1S)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-2-pyridinamine |
| Purity: | ≥98% |
Potent and selective MTH1 inhibitor
| Chemical Name: | N-Ethyl-4-[(3S)-3-methyl-4-morpholinyl]-1H-pyrrolo[2,3-b]pyridine-2-carboxamide |
| Purity: | ≥98% |
Degrader of MTH1 fusion proteins for use within the aTAG system
| Alternate Names: | CFT 2139 |
| Chemical Name: | 6-(6-((4-(2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)butyl)carbamoyl)pyridin-3-yl)-N-methyl-4-(phenylamino)quinoline-3-carboxamide |
| Purity: | ≥98% |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #AT3B3 |
| Applications: | WB, ELISA, Flow, ICC/IF |
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #23GB4060 |
| Applications: | WB, Flow, ICC/IF, Mycoplasma |
| Reactivity: | Human |
| Applications: | WB |
| Reactivity: | Human |
| Applications: | WB |
| Reactivity: | Human |
| Applications: | WB |
| Reactivity: | Human |
| Applications: | WB |
| Reactivity: | Human |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #0P6T10 |
| Applications: | WB |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #S06-8A6 |
| Applications: | WB |
| Reactivity: | Human |
| Source: | E. coli |
| Applications: | PAGE |
| Reactivity: | Human |
| Source: | E. coli |
| Applications: | AC |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ELISA |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | KO, IHC, WB, ICC/IF, Mycoplasma, + 1 More |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | KO, IHC, WB, ICC/IF, Mycoplasma, + 1 More |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | KO, IHC, WB, ICC/IF, Mycoplasma, + 1 More |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | KO, IHC, WB, ICC/IF, Mycoplasma, + 1 More |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | KO, IHC, WB, ICC/IF, Mycoplasma, + 1 More |