5 results for "Nicotinic Acetylcholine R alpha 3/CHRNA3 Small Molecules and Peptides" in Products
Nicotinic Acetylcholine R alpha 3/CHRNA3 Small Molecules and Peptides
The nicotinic acetylcholine receptor (nAChR) is a ligand gated ion channel that mediates neurotransmission at the neuromuscular junction, autonomic ganglia and at some sites in the central nervous system. Distinct nAChR subtypes exist that can be stimulated by the neurotransmitter acetylcholine, the natural product nicotine, or by synthetic compounds. After binding acetylcholine, Nicotinic Acetylcholine Receptor alpha 3 responds by an extensive change in conformation that affects all subunits and leads to opening of an ion conducting channel across the plasma membrane.
Non-competitive nAChR antagonist
| Chemical Name: | (1R,2S,4S)-rel-N,2,3,3-Tetramethylbicyclo[2.2.1]heptan-2-amine hydrochloride |
Potent and selective neuronal nAChRagonist
| Chemical Name: | (1R,5S)-1,2,3,4,5,6-hexahydro-1,5-methano-8H-pyrido[1,2-a][1,5]diazocin-8-one |
| Purity: | ≥99% |
Selective α3β4 nAChR antagonist
| Chemical Name: | 1,3-Dihydro-1-(3-exo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-2H-indol-2-one |
| Purity: | ≥98% |
α3β2 full agonist; also α3β4 partial agonist
| Chemical Name: | 3-(3-Bromo-2-thienyl)-8-methyl-8-azabicyclo[3.2.1]oct-2-ene fumarate |
| Purity: | ≥98% |
Selective α4β2 nAChR agonist
| Alternate Names: | Tebanicline |
| Chemical Name: | (R)-5-(Azetidin-2-ylmethoxy)-2-chloropyridine hydrochloride |
| Purity: | ≥98% |
