3 results for "NMDA Receptor Antagonists" in Products

NMDA Receptor Antagonists

NMDA receptors are expressed alongside AMPA receptors on the postsynaptic membrane of excitatory synapses, where they initiate a two-component excitatory postsynaptic potential (EPSP). The activation of AMPA receptors produces a current that has rapid onset and decay, while activation of NMDA receptors leads to a current with slower onset and decay. The slow decay of NMDA-mediated currents is due to the slow dissociation of glutamate from NMDA receptors, compared with AMPA receptors. Unlike ...

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Potent kynurenine 3-monooxygenase (KMO) inhibitor

Chemical Name: 3,4-Dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]benzenesulfonamide
Purity: ≥98%
Potent kynurenine 3-monooxygenase (KMO) inhibitor
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Potent competitive inhibitor of L-glutamate uptake

Chemical Name: 7-Chloro-4-hydroxyquinoline-2-carboxylic acid
Purity: ≥98%
Potent competitive inhibitor of L-glutamate uptake
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Potent competitive inhibitor of L-glutamate uptake. Sodium salt of 7-Chlorokynurenic acid (Cat. No. 0237)

Chemical Name: 7-Chloro-4-hydroxyquinoline-2-carboxylic acid sodium salt
Purity: ≥98%
Potent competitive inhibitor of L-glutamate uptake. Sodium salt of 7-Chlorokynurenic acid (Cat. No. 0237)
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