NMDA receptor antagonist acting at the glycine site. Potent competitive inhibitor of L-glutamate transport into synaptic vesicles. Also available as part of the NMDA Receptor - Glycine Site Tocriset™
. 7-Chlorokynurenic acid sodium salt
(Cat. No. 3697) also available.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Other Product-Specific Information:
Synthesis of S-[3-(4(5)-imidazolyl)propyl]-N-[2-(4-[125I]-iodophenylethyl]isothiourea sulfate [125I]-iodophenpropit), a new probe for histamine H3 receptor binding sites.
Menge et al.
J.Labelled Comp.Radiopharm. XXXI, 1992;10:781
Substituted quinolines as inhibitors of L-glutamate transport into synaptic vesicles.
Bartlett et al.
7-Chlorokynurenic acid is a selective antagonist of the glycine modulatory site of the NMDA receptor complex.
Kemp et al.
Behavioral and neurochemical actions of the strychnine-insensitive glycine receptor antagonist, 7-chlorokynurenate, in rats.
Kretschmer et al.
The citations listed below are publications that use Tocris products. Selected citations for 7-Chlorokynurenic acid include:
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