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3 results for "NUAK Inhibitors" in Products
NUAK Inhibitors
NUAKs are AMPK-related kinases (ARK) and members of the calcium/calmodulin-dependent protein kinase-like (CAMKL) family of enzymes. Two NUAKs have been described, NUAK1 (ARK5) and NUAK2 (SNARK), both of which are 76kDa proteins containing an ubiquitin-associated domain located next to the C-terminal of the catalytic domain, which is required for liver kinase B1 (LKB1, also known as serine/threonine kinase 11) phosphorylation and activation. Myosin phosphatase complex subunit (MYPT1) is a ...
| Chemical Name: | N-3-[[5-Chloro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]oxy]phenyl]propanamide |
| Purity: | ≥98% |
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| Chemical Name: | 5,13-Dihydro-4,5,13-trimethyl-2-[[1-(4-piperidinyl)-1H-pyrazol-4-yl]amino]-6H-naphtho[2,3-e]pyrimido[5,4-b][1,4]diazepin-6-one |
| Purity: | ≥98% |
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| Chemical Name: | (R)-7-(Imidazo[1,2-b]pyridazin-3-yl)-3-(6-methyl-2,6-diazaspiro[3.3]heptan-2-yl)-1-(1-phenylethyl)pyrido[3,4-b]pyrazin-2(1H)-one |
| Purity: | ≥98% |
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