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5 results for "PDE5A" in Products
PDE5A Products
PDE5A encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.
PDE inhibitor (non-selective)
| Chemical Name: | 3,7-Dihydro-1-methyl-3-(2-methylpropyl)-1H-purine-2,6-dione |
| Purity: | ≥98% |
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Adenosine transport inhibitor
| Chemical Name: | 2,6-bis(Diethanolamino)-4,8-dipiperidinopyrimido[5,4-d]pyrimidine |
| Purity: | ≥98% |
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USP10 and USP13 inhibitor; inhibits autophagy
| Chemical Name: | 6-Fluoro-N-[(4-Fluorophenyl)methyl]-4-quinazolinamine |
| Purity: | ≥98% |
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Potent PDE5 inhibitor; orally active
| Chemical Name: | 1-[[3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methylpiperazine citrate |
| Purity: | ≥98% |
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Potent and highly selective PDE5 inhibitor; orally bioavailable
| Alternate Names: | GF196960 |
| Chemical Name: | (6R,12aR)-6-(1,3-Benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methylpyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione |
| Purity: | ≥98% |
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