4 results for "S1P2/EDG-5 Small Molecules and Peptides" in Products

S1P2/EDG-5 Small Molecules and Peptides

EDG molecules are G protein-coupled receptors that bind plasma lysophospholipids. The EDG family consists of two subfamilies; the S1P (sphingosine-1-phosphate) subfamily consisting of EDG-1, 3, 5, 6, and 8, and the LPA (lysophosphatidic acid) subfamily that contains EDG-2, 4 and 7. Each receptor is the product of a distinct gene. The S1P family reg...

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S1P2 receptor antagonist

Chemical Name: 1-[1,3-Dimethyl-4-(2-methylethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]-4-(3,5-dichloro-4-pyridinyl)-semicarbazide
Purity: ≥98%
S1P2 receptor antagonist
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Endogenous agonist at S1P1-5

Chemical Name: (E)-D-erythro-2-amino-1-(dihydrogenphosphate)-4-octadecene-1,3-diol
Purity: ≥98%
Endogenous agonist at S1P1-5
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Potent S1P receptor agonist; also immunosuppressant

Alternate Names: Fingolimod,Gilenya
Chemical Name: 2-Amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol hydrochloride
Purity: ≥98%
Potent S1P receptor agonist; also immunosuppressant
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Selective S1P2 allosteric agonist

Chemical Name: 1-[2-[2,5-Dimethyl-1-(phenylmethyl)-1H-pyrrol-3-yl]-2-oxoethyl]-1,6-dihydro-6-oxo-3-pyridinecarbonitrile
Purity: ≥98%
Selective S1P2 allosteric agonist
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