220 results for "VHL" in Products
VHL Products
Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2B Monoclonal Clone #OTI1E1 |
| Applications: | IHC, WB |
![Western Blot: Von Hippel Lindau Antibody (OTI1E1) [NBP2-45411]](https://resources.rndsystems.com/images/products/Von-Hippel-Lindau-Antibody-1E1-Western-Blot-NBP2-45411-img0008.jpg "Western Blot: Von Hippel Lindau Antibody (OTI1E1) [NBP2-45411]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2B Monoclonal Clone #OTI1E1 |
| Applications: | IHC, WB |
![Western Blot: Von Hippel Lindau Antibody (OTI1E1)Azide and BSA Free [NBP2-74851]](https://resources.rndsystems.com/images/products/Von-Hippel-Lindau-Antibody-OTI1E1-Azide-and-BSA-Free-Western-Blot-NBP2-74851-img0001.jpg "Western Blot: Von Hippel Lindau Antibody (OTI1E1)Azide and BSA Free [NBP2-74851]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB, ELISA |
![Western Blot: Von Hippel Lindau Antibody [NB100-41384]](https://resources.rndsystems.com/images/products/Von-Hippel-Lindau-Antibody-Western-Blot-NB100-41384-img0003.jpg "Western Blot: Von Hippel Lindau Antibody [NB100-41384]")
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: Von Hippel Lindau Antibody [H00007428-D01P]](https://resources.rndsystems.com/images/products/Von-Hippel-Lindau-Antibody-Western-Blot-H00007428-D01P-img0004.jpg "Western Blot: Von Hippel Lindau Antibody [H00007428-D01P]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #1066402 |
| Applications: | WB, Simple Western |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #1066409 |
| Applications: | IHC |
| Reactivity: | Human, Mouse, Rat, Primate |
| Details: | Rabbit Polyclonal |
| Applications: | IHC, WB, ELISA, IP |
![Immunohistochemistry-Paraffin: Von Hippel Lindau Antibody [NBP3-12365]](https://resources.rndsystems.com/images/products/Von-Hippel-Lindau-Antibody-Immunohistochemistry-Paraffin-NBP3-12365-img0003.jpg "Immunohistochemistry-Paraffin: Von Hippel Lindau Antibody [NBP3-12365]")
Negative Control for MZ 1 (Cat. No. 6154)
| Chemical Name: | (2S,4S)-1-((S)-2-(tert-butyl)-17-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-4,16-dioxo-6,9,12-trioxa-3,15-diazaheptadecanoyl)- 4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide |
| Purity: | ≥98% |
VHL ligand with alkyl linker and terminal amine for onward chemistry
| Alternate Names: | (S,R,S)-AHPC-C2-NH2 |
| Chemical Name: | (2S,4R)-1-((S)-2-(3-Aminopropanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide dihydrochloride |
| Purity: | ≥95% |
VHL ligand with PEG linker and terminal amine for onward chemistry
| Alternate Names: | (S,R,S)-AHPC-PEG2-NH2 |
| Chemical Name: | (2S,4R)-1-((S)-2-(2-(2-(2-Aminoethoxy)ethoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide |
| Purity: | ≥95% |
VHL ligand with alkyl linker and terminal amine for onward chemistry
| Alternate Names: | (S,R,S)-AHPC-C5-NH2 |
| Chemical Name: | (2S,4R)-1-((S)-2-(6-Aminohexanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide dihydrochloride |
| Purity: | ≥95% |
VHL ligand with alkyl linker and terminal acid for onward chemistry
| Alternate Names: | (S,R,S)-AHPC-C2-COOH |
| Chemical Name: | 4-(((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-4-oxobutanoic acid |
| Purity: | ≥95% |
VHL ligand with alkyl linker and terminal amine for onward chemistry
| Chemical Name: | (2S,4R)-N-(2-(4-Aminobutoxy)-4-(4-methylthiazol-5-yl)benzyl)-1-((S)-2-(1-fluorocyclopropane-1-carboxamido)-3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxamide dihydrochloride |
| Purity: | ≥95% |
VHL ligand with alkyl linker and terminal amine for onward chemistry
| Chemical Name: | (2S,4R)-N-(2-((6-Aminohexyl)oxy)-4-(4-methylthiazol-5-yl)benzyl)-1-((S)-2-(1-fluorocyclopropane-1-carboxamido)-3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxamide dihydrochloride |
| Purity: | ≥95% |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #1066408 |
| Applications: | ICC/IF |
Functionalized VHL ligand for PROTACs
| Chemical Name: | (4R)-3-Methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-L-prolinamide dihydrochloride |
| Purity: | ≥98% |
VHL ligand with PEG linker and terminal amine for onward chemistry
| Alternate Names: | (S,R,S)-AHPC-PEG3-NH2 |
| Chemical Name: | (2S,4R)-1-((S)-14-amino-2-(tert-butyl)-4-oxo-6,9,12-trioxa-3-azatetradecan-1-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide dihydrochloride |
| Purity: | ≥95% |
VHL ligand with PEG linker and terminal amine for onward chemistry
| Alternate Names: | (S,R,S)-AHPC-PEG4-NH2 |
| Chemical Name: | (2S,4R)-1-((S)-17-Amino-2-(tert-butyl)-4-oxo-6,9,12,15-tetraoxa-3-azaheptadecan-1-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide dihydrochloride |
| Purity: | ≥95% |
VHL ligand with alkyl linker and terminal amine for onward chemistry
| Alternate Names: | (S,R,S)-AHPC-C4-NH2 |
| Chemical Name: | (2S,4R)-1-((S)-2-(5-aminopentanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide dihydrochloride |
| Purity: | ≥95% |
VHL ligand with PEG linker and terminal acid for onward chemistry
| Alternate Names: | (S,R,S)-AHPC-PEG3-COOH |
| Chemical Name: | (S)-15-((2S,4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidine-1-carbonyl)-16,16-dimethyl-13-oxo-4,7,10-trioxa-14-azaheptadecanoic acid |
| Purity: | ≥95% |
VHL ligand with alkyl linker and terminal acid for onward chemistry
| Alternate Names: | (S,R,S)-AHPC-C4-COOH |
| Chemical Name: | 6-(((S)-1-((2S,4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-6-oxohexanoic acid |
| Purity: | ≥95% |
Alkyne-functionalized VH 032; 'click' VHL ligand for PROTACs
| Chemical Name: | (2S,4R)-1-((S)-3,3-Dimethyl-2-(2-(prop-2-yn-1-yloxy)acetamido)butanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide |
| Purity: | ≥95% |
VHL ligand with alkyl linker and terminal amine for onward chemistry
| Alternate Names: | VH 032 - linker 8,(S,R,S)-AHPC-C2-NH2 |
| Chemical Name: | (2S,4R)-1-((S)-2-(7-Aminoheptanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide dihydrochloride |
| Purity: | ≥95% |
VHL ligand with PEG linker and terminal amine for onward chemistry
| Alternate Names: | (S,R,S)-AHPC-PEG1-NH2 |
| Chemical Name: | (2S,4R)-1-((S)-2-(2-(2-Aminoethoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide dihydrochloride |
| Purity: | ≥95% |
VHL ligand with alkyl linker and terminal amine for onward chemistry
| Alternate Names: | (S,R,S)-AHPC-C10-NH2 |
| Chemical Name: | (2S,4R)-1-((S)-2-(11-Aminoundecanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide dihydrochloride |
| Purity: | ≥95% |
