Argininosuccinate Lyase Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-87462

Novus Biologicals
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human, Canine

Cited:

Mouse, Canine

Predicted:

Mouse (92%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

Western Blot, IF/IHC

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all Argininosuccinate Lyase Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: MASESGKLWGGRFVGAVDPIMEKFNASIAYDRHLWEVDVQGSKAYSRGLEKAGLLTKAEMDQILHGLDKVAEEWAQGTFKLNSNDED

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Rat (86%). Canine reactivity reported in scientific literature (PMID: 24945279).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Argininosuccinate Lyase Antibody - BSA Free

Immunohistochemistry-Paraffin: Argininosuccinate Lyase Antibody [NBP1-87462]

Immunohistochemistry-Paraffin: Argininosuccinate Lyase Antibody [NBP1-87462]

Immunohistochemistry-Paraffin: Argininosuccinate Lyase Antibody [NBP1-87462] - Staining in human liver and skeletal muscle tissues using NBP1-87462 antibody. Corresponding ASL RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: Argininosuccinate Lyase Antibody [NBP1-87462]

Immunohistochemistry-Paraffin: Argininosuccinate Lyase Antibody [NBP1-87462]

Immunohistochemistry-Paraffin: Argininosuccinate Lyase Antibody [NBP1-87462] - Staining of human kidney shows moderate to strong cytoplasmic positivity in cells in tubules.
Immunohistochemistry-Paraffin: Argininosuccinate Lyase Antibody [NBP1-87462]

Immunohistochemistry-Paraffin: Argininosuccinate Lyase Antibody [NBP1-87462]

Immunohistochemistry-Paraffin: Argininosuccinate Lyase Antibody [NBP1-87462] - Staining of human liver shows strong cytoplasmic positivity in hepatocytes.
Immunohistochemistry-Paraffin: Argininosuccinate Lyase Antibody [NBP1-87462]

Immunohistochemistry-Paraffin: Argininosuccinate Lyase Antibody [NBP1-87462]

Immunohistochemistry-Paraffin: Argininosuccinate Lyase Antibody [NBP1-87462] - Staining of human skeletal muscle shows no positivity in myocytes as expected.
Immunohistochemistry-Paraffin: Argininosuccinate Lyase Antibody [NBP1-87462]

Immunohistochemistry-Paraffin: Argininosuccinate Lyase Antibody [NBP1-87462]

Immunohistochemistry-Paraffin: Argininosuccinate Lyase Antibody [NBP1-87462] - Staining of human stomach shows weak cytoplasmic positivity in glandular cells.

Applications for Argininosuccinate Lyase Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000-1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Argininosuccinate Lyase

Argininosuccinate Lyase encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency. A nontranscribed pseudogene is also located on the long arm of chromosome 22. Alternatively spliced transcript variants encoding different isoforms have been described.

Alternate Names

argininosuccinase, argininosuccinate lyase, Arginosuccinase, ASAL, EC 4.3.2.1

Gene Symbol

ASL

Additional Argininosuccinate Lyase Products

Product Documents for Argininosuccinate Lyase Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for Argininosuccinate Lyase Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for Argininosuccinate Lyase Antibody - BSA Free

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Protocols

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