Canine IL-3 Alexa Fluor® 405-conjugated Antibody

Catalog #: FAB6658V Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
FAB6658V-100UG

Save 15% on Select RUO Reagents. See Details.

All IL-3 Antibodies

Product Details

Supplemental Products

Reviews

Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Canine IL-3 Alexa Fluor® 405-conjugated Antibody Summary

Species Reactivity

Canine

Specificity

Detects canine IL-3 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant IL-3 from human, mouse, or rat is observed.

Source

Monoclonal Mouse IgG1 Clone # 662008

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant canine IL-3
Arg24-Pro143
Accession # Q9BDX4

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 405 (Excitation= 405 nm, Emission= 421 nm)

Applications

Recommended Concentration

Sample

Immunocytochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: IL-3

Interleukin-3 is a pleiotrophic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenitors. IL-3 exerts its biological activities via a heterodimeric receptor composed of an IL-3 specific alpha chain and common beta chain that is shared with the IL-5 and GM-CSF high-affinity receptors. Receptors for IL-3 are present on bone marrow progenitors, and several mature myeloid cell types. Mature canine IL-3 shares <40% amino acid sequence identity with IL-3 of other mammals.

Long Name

Interleukin 3

Entrez Gene IDs

3562 (Human); 16187 (Mouse); 24495 (Rat)

Alternate Names

Hematopoietic growth factor; IL3; IL-3; IL-3MGC79398; interleukin 3 (colony-stimulating factor, multiple); interleukin-3; Mast cell growth factor; mast-cell growth factor; MCGF; MCGFMGC79399; MULTI-CSF; multilineage-colony-stimulating factor; Multipotential colony-stimulating factor; P-cell stimulating factor; P-cell-stimulating factor