CD2BP2 Antibody

Novus Biologicals | Catalog # NB100-1526

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (100%), Canine (100%), Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Western Blot, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
View all CD2BP2 Primary Antibodies »

Product Specifications

Immunogen

Peptide with sequence PKRKVTFQGVGDE-C corresponding to N-Terminus according to NP_006101.1.

Epitope

N Terminus

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for CD2BP2 Antibody

Western Blot: CD2BP2 Antibody [NB100-1526]

Western Blot: CD2BP2 Antibody [NB100-1526]

Western Blot: CD2BP2 Antibody [NB100-1526] - (0.3ug/ml) staining of Human Thymus lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for CD2BP2 Antibody

Application
Recommended Usage

Immunohistochemistry

5 - 10 ug/ml

Peptide ELISA

Detection limit 1:32000

Western Blot

0.3 - 10 ug/ml
Application Notes
WB: Approx. 50 kDa band observed in human lymph node, thymus and tonsil lysates (calculated MW of 37.6 kDa band according to NP_006101.1). The observed molecular weights correspond to earlier findings is reported in scientific literature with different antibodies (Nishizawa et al, Proc Natl Acad Sci U S A. 1998 Dec 8;95(25): 14897-902). IHC-P: Human spleen shows nucleolar staining in select splenocytes.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: CD2BP2

CD2BP2 is an intracellular protein which binds to a site containing two PPPGHR segments within the cytoplasmic region of CD2. Mutagenesis and NMR analysis demonstrated that the CD2 binding region of CD2BP2 includes a 17 amino acid motif also found in several yeast and Caenorhabditis elegans proteins of unknown function. In Jurkat T cells, over expression of the isolated CD2BP2 domain binding to CD2 enhances the production of interleukin 2 on crosslinking of CD2 but not the T cell receptor.

Alternate Names

CD2 (cytoplasmic tail) binding protein 2, CD2 antigen (cytoplasmic tail) binding protein 2, CD2 antigen (cytoplasmic tail)-binding protein 2, CD2 antigen cytoplasmic tail-binding protein 2, CD2 binding protein 2, CD2 cytoplasmic domain binding protein 2, CD2 cytoplasmic domain-binding protein 2, CD2 tail-binding protein 2, FWP010, KIAA1178, LIN1, Snu40, U5 snRNP 52K protein, U5-52K

Entrez Gene IDs

10421 (Human); 70233 (Mouse)

Gene Symbol

CD2BP2

UniProt

NP_006101.1 (Human)

Additional CD2BP2 Products

Product Documents for CD2BP2 Antibody

Certificate of Analysis

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Product Specific Notices for CD2BP2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for CD2BP2 Antibody

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Protocols

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