Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry-Paraffin, ELISA, Protein Array

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # C3D/2891

Format

Azide and BSA Free
View all Complement C3d Primary Antibodies »

Product Specifications

Immunogen

Recombinant fragment (around aa 1250-1450) of human Complement C3d protein (exact sequence is proprietary) (Uniprot: P01024)

Localization

Plasma.

Marker

Acute Humoral Rejection Marker

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Description

1.0 mg/ml of antibody purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS WITHOUT BSA & azide. Also available at 200 ug/ml WITH BSA & azide (NBP3-07741).

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80 C.

Scientific Data Images for Complement C3d Antibody (C3D/2891) - Azide and BSA Free

Immunohistochemistry-Paraffin: Complement C3d Antibody (C3D/2891) - Azide and BSA Free [NBP3-08764]

Immunohistochemistry-Paraffin: Complement C3d Antibody (C3D/2891) - Azide and BSA Free [NBP3-08764]

Immunohistochemistry-Paraffin: Complement C3d Antibody (C3D/2891) - Azide and BSA Free [NBP3-08764] - Formalin-fixed, paraffin-embedded human hepatocellular carcinoma stained with Complement C3d Antibody (C3D/2891) at 2ug/ml. HIER: Tris/EDTA, pH9.0, 45min. HRP-polymer, 30min. DAB, 5min.
Immunohistochemistry-Paraffin: Complement C3d Antibody (C3D/2891) - Azide and BSA Free [NBP3-08764]

Immunohistochemistry-Paraffin: Complement C3d Antibody (C3D/2891) - Azide and BSA Free [NBP3-08764]

Immunohistochemistry-Paraffin: Complement C3d Antibody (C3D/2891) - Azide and BSA Free [NBP3-08764] - Formalin-fixed, paraffin-embedded human rejected kidney transplant stained with Complement C3d Antibody (C3D/2891) at 2ug/ml in PBS. HIER: Tris/EDTA, pH9.0, 45min. HRP-polymer, 30min. DAB, 5min.
Protein Array: Complement C3d Antibody (C3D/2891) - Azide and BSA Free [NBP3-08764]

Protein Array: Complement C3d Antibody (C3D/2891) - Azide and BSA Free [NBP3-08764]

Protein Array: Complement C3d Antibody (C3D/2891) - Azide and BSA Free [NBP3-08764] - Analysis of Protein Array containing more than 19,000 full-length human proteins using Complement C3d Mouse Monoclonal Antibody (C3D/2891).

Applications for Complement C3d Antibody (C3D/2891) - Azide and BSA Free

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Protein Array

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
ELISA: For coating, order antibody without BSA

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10 mM PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20 to -80C. Avoid freeze-thaw cycles.

Background: Complement C3d

C3d is a fragment of the major complement protein C3, C3d is formed as a result of the deactivation of C3b.Factor I in the presence of cofactors cleaves C3b to form iC3b and C3f, Factor I and/or other proteasesthen cleaves iC3b to form C3c and C3dg. C3dg is then further cleaved by tryptic enzymes to C3g andC3d. The C3 fragments are then eliminated from circulation by phagocytic cells in the liver. C3d has amolecular weight of 34kDa. Normally C3d is present in trace amounts in plasma, however, in diseasestates where rapid complement consumption is occurring levels of C3d can be elevated.

Alternate Names

AHUS5, ARMD9, ASP, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, complement C3, complement component 3, complement component C3, CPAMD1acylation-stimulating protein cleavage product

Gene Symbol

C3

Additional Complement C3d Products

Product Documents for Complement C3d Antibody (C3D/2891) - Azide and BSA Free

Certificate of Analysis

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Product Specific Notices for Complement C3d Antibody (C3D/2891) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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