Human DDX17 Alexa Fluor® 350-conjugated Antibody

Catalog #: AF4530U Datasheet / COA / SDS

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AF4530U-100UG

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Human DDX17 Alexa Fluor® 350-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human DDX17 in Western blots.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

E. coli-derived recombinant human DDX17
Asn498-Tyr638
Accession # Q92841

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 350 (Excitation= 346 nm, Emission= 442 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilution of this antibody should be experimentally determined.

Immunocytochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: DDX17

DDX17 is a member of the DEAD box family of proteins, a family of RNA helicases characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD). DDX17 plays an essential role in many aspects of cellular RNA metabolism, including RNA transport, transcription, ribosome assembly, spliceosome function, RNA degradation, and the initiation of translation. Distribution patterns suggests that some members of this family may be involved in spermatogenesis, embryogenesis, and cellular growth and division. Alternative splicing of the DDX17 gene generates two transcript variants encoding isoforms p72 and p82. p82 is translated from a non-AUG start codon 243 bp upstream of the first in frame AUG initiator codon for p72. DDX17 is more closely related to DDX5 than to any other member of the DEAD box family.

Long Name

DEAD Box Protein 17

Entrez Gene IDs

10521 (Human); 67040 (Mouse); 315133 (Rat)

Alternate Names

DDX17; DEAD (Asp-Glu-Ala-Asp) box polypeptide 17; DEAD box protein 17; DEAD box protein p72; DEAD/H box 17; DKFZp761H2016; EC 3.6.1; EC 3.6.4.13; p72; P72DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 17 (72kD); probable ATP-dependent RNA helicase DDX17; RH70; RNA-dependent helicase p72