Human EPCR Antibody
R&D Systems | Catalog # MAB22451
Key Product Details
Species Reactivity
Validated:
Cited:
Applications
Validated:
Cited:
Label
Antibody Source
Product Specifications
Immunogen
Ser18-Ser210
Accession # Q9UNN8
Specificity
Clonality
Host
Isotype
Scientific Data Images for Human EPCR Antibody
EPCR in Human Skin.
EPCR was detected in immersion fixed paraffin-embedded sections of human skin using 25 µg/mL Mouse Anti-Human EPCR Monoclonal Antibody (Catalog # MAB22451) overnight at 4 °C. Tissue was stained with the Anti-Mouse HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS002) and counterstained with hematoxylin (blue). View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.
Detection of EPCR by Immunohistochemistry
PROCR expression pattern in Normal-Healthy, NATs, and breast tumors. A Representative IHC of PROCR in Normal-Healthy, NATs, and/or tumors of women of AA and EA. b Enlarged view of PROCR expression in Normal-Healthy and tumor. c Differences in PROCR expression (positivity and H-score) between Normal-Healthy tissues of women of AA and EA. Differences in PROCR expression (positivity *p = 2.2051E−8 and H-score *p = 6.0538E−9) between Normal-Healthy tissues of AA and EA. The statistical test that was utilized to analyze the data was two-sided Wilcoxon Test. d Differences in PROCR expression (positivity and H-score) between Normal-Healthy and NATs of women of AA and EA (positivity *p = 4.588E−11 and H-score *p = 1.4572E−11). The data were analyzed using two-sided Wilcoxon test. e Differences in PROCR expression (positivity and H-score) between NATs and tumors of women of AA and EA. Data were analyzed using two-sided Wilcoxon test. (Normal-Healthy-AA (n = 31), and EA (n = 129); NAT -AA (n = 35) and EA (n = 31); Tumor -AA (n = 41) and EA (n = 62)). Depending on availability, two cores of same NAT and tumor were included in the TMA. Dot blots in this and subsequent relevant figures include values from both cores of the same sample. All the data points are shown as mean ± SD. Source data are provided as a Source Data file. Image collected and cropped by CiteAb from the following open publication (https://pubmed.ncbi.nlm.nih.gov/37709737), licensed under a CC-BY license. Not internally tested by R&D Systems.Applications for Human EPCR Antibody
Immunohistochemistry
Sample: Immersion fixed paraffin-embedded sections of human skin
Western Blot
Sample: Recombinant Human EPCR
Formulation, Preparation, and Storage
Purification
Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
Formulation
Shipping
Stability & Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Calculators
Background: EPCR
Long Name
Alternate Names
Gene Symbol
UniProt
Additional EPCR Products
Product Documents for Human EPCR Antibody
Product Specific Notices for Human EPCR Antibody
For research use only
Related Research Areas
Citations for Human EPCR Antibody
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Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
- Antigen Retrieval Protocol (PIER)
- Antigen Retrieval for Frozen Sections Protocol
- Appropriate Fixation of IHC/ICC Samples
- Cellular Response to Hypoxia Protocols
- Chromogenic IHC Staining of Formalin-Fixed Paraffin-Embedded (FFPE) Tissue Protocol
- Chromogenic Immunohistochemistry Staining of Frozen Tissue
- Detection & Visualization of Antibody Binding
- Fluorescent IHC Staining of Frozen Tissue Protocol
- Graphic Protocol for Heat-induced Epitope Retrieval
- Graphic Protocol for the Preparation and Fluorescent IHC Staining of Frozen Tissue Sections
- Graphic Protocol for the Preparation and Fluorescent IHC Staining of Paraffin-embedded Tissue Sections
- Graphic Protocol for the Preparation of Gelatin-coated Slides for Histological Tissue Sections
- IHC Sample Preparation (Frozen sections vs Paraffin)
- Immunofluorescent IHC Staining of Formalin-Fixed Paraffin-Embedded (FFPE) Tissue Protocol
- Immunohistochemistry (IHC) and Immunocytochemistry (ICC) Protocols
- Immunohistochemistry Frozen Troubleshooting
- Immunohistochemistry Paraffin Troubleshooting
- Preparing Samples for IHC/ICC Experiments
- Preventing Non-Specific Staining (Non-Specific Binding)
- Primary Antibody Selection & Optimization
- Protocol for Heat-Induced Epitope Retrieval (HIER)
- Protocol for Making a 4% Formaldehyde Solution in PBS
- Protocol for VisUCyte™ HRP Polymer Detection Reagent
- Protocol for the Preparation & Fixation of Cells on Coverslips
- Protocol for the Preparation and Chromogenic IHC Staining of Frozen Tissue Sections
- Protocol for the Preparation and Chromogenic IHC Staining of Frozen Tissue Sections - Graphic
- Protocol for the Preparation and Chromogenic IHC Staining of Paraffin-embedded Tissue Sections
- Protocol for the Preparation and Chromogenic IHC Staining of Paraffin-embedded Tissue Sections - Graphic
- Protocol for the Preparation and Fluorescent IHC Staining of Frozen Tissue Sections
- Protocol for the Preparation and Fluorescent IHC Staining of Paraffin-embedded Tissue Sections
- Protocol for the Preparation of Gelatin-coated Slides for Histological Tissue Sections
- R&D Systems Quality Control Western Blot Protocol
- TUNEL and Active Caspase-3 Detection by IHC/ICC Protocol
- The Importance of IHC/ICC Controls
- Troubleshooting Guide: Immunohistochemistry
- Troubleshooting Guide: Western Blot Figures
- Western Blot Conditions
- Western Blot Protocol
- Western Blot Protocol for Cell Lysates
- Western Blot Troubleshooting
- Western Blot Troubleshooting Guide
- View all Protocols, Troubleshooting, Illustrated assays and Webinars