Human INSRR Antibody [Biotin]

R&D Systems | Catalog # BAF3055

R&D Systems

Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Biotin

Antibody Source

Polyclonal Goat IgG
View all INSRR Primary Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human INSRR
Leu24-Leu923
Accession # P14616

Specificity

Detects human INSRR in Western blots. In Western blots, less than 1% cross-reactivity with recombinant human INSR is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Human INSRR Antibody [Biotin]

Application
Recommended Usage

Western Blot

0.1 µg/mL
Sample: Recombinant Human INSRR

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: INSRR

INSRR is a 175 kDa orphan receptor belonging to the insulin receptor subfamily of the receptor tyrosine kinase family. It is synthesized as a single chain type I transmembrane glycoprotein precursor and undergoes proteolytic processing to generate the mature disulfide linked alpha 2/ beta 2 tetrameric receptor. The alpha subunit is localized extracellularly while the transmembrane beta subunit contains an extracellular domain, a transmembrane segment and a cytoplasmic kinase domain. A ligand for INSRR has not yet been identified. The extracellular domain of human INSRR shares approximately 90% amino acid sequence homology with the mouse protein.

Long Name

Insulin Receptor-related Receptor

Alternate Names

IRR

Entrez Gene IDs

3645 (Human); 23920 (Mouse)

Gene Symbol

INSRR

UniProt

P14616

Additional INSRR Products

Product Documents for Human INSRR Antibody [Biotin]

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human INSRR Antibody [Biotin]

For research use only

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