Human/Mouse Orexin A/Hypocretin-1 Alexa Fluor® 488-conjugated Antibody

Catalog #: FAB763G Datasheet / COA / SDS

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FAB763G-100UG

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Human/Mouse Orexin A/Hypocretin-1 Alexa Fluor® 488-conjugated Antibody Summary

Species Reactivity

Human, Mouse

Specificity

Detects human and mouse Orexin A/Hypocretin‑1. In dot blots, no cross-reactivity with recombinant human Orexin B is observed.

Source

Monoclonal Mouse IgG1 Clone # 97505

Purification

Protein A or G purified

Immunogen

KLH-coupled human Orexin A/Hypocretinâ€‘1 synthetic peptide
Accession # O43612

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 488 (Excitation= 488 nm, Emission= 515-545 nm)

Applications

Recommended Concentration

Sample

Immunohistochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Orexin A/Hypocretin-1

Orexin A and Orexin B are neuropeptide hormones derived from proteolytic processing of the Orexin precursor protein. Orexins are released from the hypothalamus and are involved in the regulation of sleeping patterns, feeding, and metabolism. The synthetic peptide immunogen corresponds to amino acid 34 - 66 of the human Orexin precursor (accession #O43612) (1).

Entrez Gene IDs

3060 (Human); 25723 (Rat)

Alternate Names

HCRT; Hcrt1; hypocretin (orexin) neuropeptide precursor; Hypocretin1; Hypocretin-1; NRCLP1; Orexin A; orexin; OXHcrt; PPORX; PPOXHypocretin