Human ORF73 HHV8 Alexa Fluor® 350-conjugated Antibody

Catalog #: FAB10389U Datasheet / COA / SDS

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FAB10389U-100UG

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All ORF73 HHV8 Antibodies

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Human ORF73 HHV8 Alexa Fluor® 350-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human ORF73 HHV8 in direct ELISAs.

Source

Monoclonal Mouse IgG Clone # LN53

Purification

Protein A or G purified

Immunogen

Recombinant protein corresponding to the latent nuclear antigen-1 molecule of ORF73 HHV8

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 350 (Excitation= 346 nm, Emission= 442 nm)

Applications

Recommended Concentration

Sample

Immunohistochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: ORF73 HHV8

Lana1 (also known as ORF73 or HHV8) is a multifunctional protein that plays a role in the replication and long-term persistence of the viral episomal genome in dividing cells. Lana1 has been found to be associated with three different diseases observed in AIDS patients; kaposi's sarcoma, primary effusion lymphoma (which is a rare type of non-Hodgkin lymphoma affecting the body cavities) and multicentric Castleman's disease. To date there is much evidence to support a direct role for Lana1 in kaposi's sarcoma.

Long Name

ORF73 of Human Herpesvirus 8

Entrez Gene IDs

4961527 (Viral)

Alternate Names

HHV8GK18_gp81; LANA; LANA1; LNA; ORF73