Human ORF73 HHV8 Alexa Fluor® 750-conjugated Antibody

Catalog #: FAB10389S Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
FAB10389S-100UG

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Human ORF73 HHV8 Alexa Fluor® 750-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human ORF73 HHV8 in direct ELISAs.
Source
Monoclonal Mouse IgG Clone # LN53
Purification
Protein A or G purified
Immunogen
Recombinant protein corresponding to the latent nuclear antigen-1 molecule of ORF73 HHV8
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 750 (Excitation= 749 nm, Emission= 775 nm)

Applications

Recommended Concentration
Sample
Immunohistochemistry
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: ORF73 HHV8

Lana1 (also known as ORF73 or HHV8)  is a multifunctional protein that plays a role in the replication and long-term persistence of the viral episomal genome in dividing cells. Lana1 has been found to be associated with three different diseases observed in AIDS patients; kaposi's sarcoma, primary effusion lymphoma (which is a rare type of non-Hodgkin lymphoma affecting the body cavities) and multicentric Castleman's disease. To date there is much evidence to support a direct role for Lana1 in kaposi's sarcoma.

Long Name
ORF73 of Human Herpesvirus 8
Entrez Gene IDs
4961527 (Viral)
Alternate Names
HHV8GK18_gp81; LANA; LANA1; LNA; ORF73

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