MOG Antibody (CL2852)

Novus Biologicals | Catalog # NBP3-52462

Recombinant Monoclonal Antibody
Novus Biologicals

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Mouse IgG1 Clone # CL2852
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Product Specifications

Immunogen

This antibody was developed using a recombinant protein derived from Q16653, with the exact immunogen sequence remaining proprietary.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for MOG Antibody (CL2852)

Immunohistochemistry-Paraffin: MOG Antibody (CL2852) [NBP3-52462]

Immunohistochemistry-Paraffin: MOG Antibody (CL2852) [NBP3-52462]

Staining of human cerebellum shows strong immunoreactivity in myelinated neural processes.
Immunohistochemistry-Paraffin: MOG Antibody (CL2852) [NBP3-52462]

Immunohistochemistry-Paraffin: MOG Antibody (CL2852) [NBP3-52462]

Staining of human cerebral cortex shows strong immunoreactivity in myelinated neural fibers.

Applications for MOG Antibody (CL2852)

Application
Recommended Usage

Immunohistochemistry

1:2500-1:5000

Immunohistochemistry-Paraffin

1:2500-1:5000

Western Blot

1 ug/ml
Application Notes
For IHC-Paraffin, we recommend using Heat-Induced Epitope Retrieval (HIER) with a pH level of 6. This optimized retrieval method ensures the best results for your experiments.

Formulation, Preparation, and Storage

Purification

Protein A purified

Reconstitution

Centrifuge the vial of lyophilized antibody at 12,000 x g for 20 seconds. Reconstitute by adding sterile, distilled water to achieve a final antibody concentration of 1mg/ml.

Formulation

Lyophilized from a 0.2 um filtered solution in PBS with Trehalose

Preservative

0.02% Sodium Azide

Concentration

LYOPH mg/ml

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: MOG

The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified.

Long Name

Myelin Oligodendrocyte Glycoprotein

Alternate Names

MGC26137, MOG Ig-AluB, MOGIG2, myelin oligodendrocyte glycoprotein, myelin-oligodendrocyte glycoprotein

Gene Symbol

MOG

Additional MOG Products

Product Documents for MOG Antibody (CL2852)

Certificate of Analysis

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Product Specific Notices for MOG Antibody (CL2852)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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