Mouse FoxN1 Alexa Fluor® 700-conjugated Antibody

Catalog #: FAB7295N Datasheet / COA / SDS

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FAB7295N-100UG

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse FoxN1 Alexa Fluor® 700-conjugated Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse FoxN1 in direct ELISAs.

Source

Monoclonal Rat IgG2a Clone # 717008

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant mouse FoxN1
Val2-Asp164
Accession # Q61575

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 700 (Excitation= 675-700 nm, Emission= 723 nm)

Applications

Recommended Concentration

Sample

Immunohistochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: FoxN1

Forkhead box N1 (FoxN1) is a 69 kDa transcriptional regulator that is primarily expressed in thymic epithelial cells and keratinocytes. FoxN1 function is required for proper T cell, hair follicle, and nail differentiation. Mutations in FoxN1 result in severe combined immunodeficiency (SCID/Nude). Mouse FoxN1 contains one DNA-binding forkhead domain (aa 271-367). Within amino acids 1 - 164, mouse FoxN1 shares 84% and 95% aa sequence identity with human and rat FoxN1, respectively.

Long Name

Forkhead Box N1

Entrez Gene IDs

8456 (Human); 15218 (Mouse); 287469 (Rat)

Alternate Names

FKHL20; forkhead box N1; forkhead box protein N1; FoxN1; RONU; Rowett nude; WHN; WHNRONU; winged helix nude; winged-helix nude; Winged-helix transcription factor nude