Mouse Laminin alpha 1 / beta 1 Alexa Fluor® 594-conjugated Antibody

Catalog #: FAB4656T Datasheet / COA / SDS

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FAB4656T-100UG

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Mouse Laminin alpha 1 / beta 1 Alexa Fluor® 594-conjugated Antibody Summary

Species Reactivity

Mouse

Specificity

Detects the Hep-1 heparin binding domain of mouse Laminin A/alpha 1 subunit (1).

Source

Monoclonal Rat IgG2a Clone # AL-4

Purification

Protein A or G purified

Immunogen

Purified fragment of chymotrypsin-digested mouse EHS tumor-derived Laminin-1

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 594 (Excitation= 590 nm, Emission= 617 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Laminin alpha 1

Laminins are heterotrimeric, non-collagenous glycoproteins composed of alpha, beta, and gamma chains. Through interactions with integrins, dystroglycan, and other receptors, Laminins contribute to cell differentation, cell shape and migration, maintenance of tissue phenotypes, and survival. Laminin-1 is comprised of alpha 1, beta 1, and gamma 1 subunits.

Entrez Gene IDs

284217 (Human); 16772 (Mouse); 316758 (Rat)

Alternate Names

LAMA; LAMA1 laminin, alpha 1 ; LAMA1; Laminin alpha 1; S-LAM-alpha