Mouse Meteorin Antibody (347504) [Biotin]

R&D Systems | Catalog # BAM34751

R&D Systems
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Key Product Details

Species Reactivity

Mouse

Applications

ELISA Detection (Matched Antibody Pair)

Label

Biotin

Antibody Source

Monoclonal Rat IgG2B Clone # 347504
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Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse Meteorin
Gly22-Asp291
Accession # Q8C1Q4

Specificity

Detects mouse Meteorin in ELISAs. In sandwich immunoassays, no cross-reactivity or interference with recombinant mouse CDNF, recombinant rat (rr) CNTF, or rrGDNF is observed.

Clonality

Monoclonal

Host

Rat

Isotype

IgG2B

Applications for Mouse Meteorin Antibody (347504) [Biotin]

Mouse Meteorin Sandwich Immunoassay

ELISA Detection (Matched Antibody Pair)
Recommended Concentration: 0.5-2 µg/mL
Use in combination with these reagents:
  • Capture Reagent: Mouse Meteorin Antibody (Catalog # MAB34752)
  • Standard: Recombinant Mouse Meteorin Protein (Catalog # 3475-MN)
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS.


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Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: Meteorin

Meteorin is a 31 kDa, secreted protein that is expressed by undifferentiated neural and glial progenitors, and astrocytes. Its name derives from it ability to generate glial cells with long meteor-like tails. Mouse Meteorin is synthesized as a 291 amino acid (aa) precursor that contains a 270 aa mature region. It contains eight cysteines with no identifiable domains or N-linked glycosylation sites. There is one alternate splice form where the first 164 aa of the precursor are deleted and aa 165 is changed to a Met, possibly to serve in translation initiation. Mature mouse Meteorin is 82% and 77% aa identical to human and bovine Meteorin, respectively.  

Alternate Names

METRN

Entrez Gene IDs

79006 (Human); 70083 (Mouse); 287151 (Rat)

Gene Symbol

METRN

UniProt

Additional Meteorin Products

Product Documents for Mouse Meteorin Antibody (347504) [Biotin]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Mouse Meteorin Antibody (347504) [Biotin]

For research use only

Related Research Areas

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