Meteorin is a 31 kDa, secreted protein that is expressed by undifferentiated neural and glial progenitors, and astrocytes. Its name derives from it ability to generate glial cells with long meteor-like tails. Mouse Meteorin is synthesized as a 291 amino acid (aa) precursor that contains a 270 aa mature region. It contains eight cysteines with no identifiable domains or N-linked glycosylation sites. There is one alternate splice form where the first 164 aa of the precursor are deleted and aa 165 is changed to a Met, possibly to serve in translation initiation. Mature mouse Meteorin is 82% and 77% aa identical to human and bovine Meteorin, respectively.
Mouse Meteorin Antibody (347504) [Biotin]
R&D Systems | Catalog # BAM34751
Key Product Details
Species Reactivity
Mouse
Applications
ELISA Detection (Matched Antibody Pair)
Label
Biotin
Antibody Source
Monoclonal Rat IgG2B Clone # 347504
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Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse Meteorin
Gly22-Asp291
Accession # Q8C1Q4
Gly22-Asp291
Accession # Q8C1Q4
Specificity
Detects mouse Meteorin in ELISAs. In sandwich immunoassays, no cross-reactivity or interference with recombinant mouse CDNF, recombinant rat (rr) CNTF, or rrGDNF is observed.
Clonality
Monoclonal
Host
Rat
Isotype
IgG2B
Applications for Mouse Meteorin Antibody (347504) [Biotin]
Mouse Meteorin Sandwich Immunoassay
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
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Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Calculators
Background: Meteorin
Alternate Names
METRN
Gene Symbol
METRN
UniProt
Additional Meteorin Products
Product Documents for Mouse Meteorin Antibody (347504) [Biotin]
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Note: Certificate of Analysis not available for kit components.
Product Specific Notices for Mouse Meteorin Antibody (347504) [Biotin]
For research use only
Related Research Areas
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