Neuropilin-2 Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-86866

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Predicted:

Mouse (96%), Rat (95%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
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Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: LSLTFHTDMAVAKDGFSARYYLVHQEPLENFQCNVPLGMESGRIANEQISASSTYSDGRWTPQQSRLHGDDNGWTPNLDSNKEYL

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Neuropilin-2

NRP2 encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F}, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

Alternate Names

Neuropilin2

Entrez Gene IDs

8828 (Human)

Gene Symbol

NRP2

UniProt

O60462 (Human)

Additional Neuropilin-2 Products

Product Documents for Neuropilin-2 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for Neuropilin-2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for Neuropilin-2 Antibody - BSA Free

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FAQs for Neuropilin-2 Antibody - BSA Free

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  • Q: Why are the bands shown in the WB different molecular weight? What is the correct size for nrp2? Are they isoforms? I think the dominant one will be 110 KD.

    A:

    It is not the wrong WB image for the NBP1-86866 antibody. This antibody is designed from sequence information in the ENSEMBL database and according to the ENSEMBL database, there is an additional isoform of 62.5 kDa. The antigen of the NBP1-86866 antibody has 100% sequence identity to this isoform as well. The isoform is called NRP2-202 (ENSP00000347238) and consists of 555 amino acids (http://www.ensembl.org/Homo_sapiens/Transcript/Summary?db=core;g=ENSG00000118257;r=2:206547224-206608421;t=ENST00000355117).

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Associated Pathways

VEGF - VEGF R2 Signaling Pathways
VEGF - VEGF R2 Signaling Pathway Thumbnail