Pepsinogen I Antibody (8003 (99/12)) - BSA Free

Novus Biologicals | Catalog # NB100-62239

Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, ELISA, Radioimmunoassay

Cited:

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 8003 (99/12)

Format

BSA Free
View all Pepsinogen I Primary Antibodies »

Product Specifications

Immunogen

Purified human pepsinogen 1

Localization

Secreted

Specificity

NB100-62239 recognises human Pepsinogen I, a zymogen or proenzyme secreted by Chief cells in the stomach. It is cleaved to form pepsin both in an autocatalytic fashion and by pepsin itself. In humans there are two related forms of pepsin, Pepsinogen I (also known as pepsinogen A), and Pepsinogen II (also known as Pepsinogen B or progastricsin).

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Pepsinogen I Antibody (8003 (99/12)) - BSA Free

Immunohistochemistry-Paraffin: Pepsinogen I Antibody (8003 (99/12)) - BSA Free [NB100-62239]

Immunohistochemistry-Paraffin: Pepsinogen I Antibody (8003 (99/12)) - BSA Free [NB100-62239]

Immunohistochemistry-Paraffin: Pepsinogen I Antibody (8003 (99/12)) [NB100-62239] - Differentiation of pyloric-gland type to fundic glands. (A) HE-stained image, showing proliferation of atypical glands associated with mildly enlarged nuclei. (B) Differentiation into fundic glands (pepsinogen-1). Tumor glands are positive for pepsinogen-1. (C) Differentiation into fundic glands (H,K-ATPase). Similar to pepsinogen-1, H,K-ATPase-positive cells can be seen in tumor glands. From: Mitsuishi T, Hamatani S, Hirooka S, Fukasawa N, Aizawa D, Hara Y, et al. (2017)

Applications for Pepsinogen I Antibody (8003 (99/12)) - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Radioimmunoassay

1:100-1:2000

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Pepsinogen I

Pepsinogen consists of a single polypeptide chain of 375 amino acids with an average molecular weight of 42 kDa. Pepsinogen I is synthesized by gastric chief cells and mucous neck cells.

Alternate Names

pepsinogen 3, group I (pepsinogen A)

Gene Symbol

PGA3

Additional Pepsinogen I Products

Product Documents for Pepsinogen I Antibody (8003 (99/12)) - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for Pepsinogen I Antibody (8003 (99/12)) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for Pepsinogen I Antibody (8003 (99/12)) - BSA Free

Customer Reviews for Pepsinogen I Antibody (8003 (99/12)) - BSA Free

There are currently no reviews for this product. Be the first to review Pepsinogen I Antibody (8003 (99/12)) - BSA Free and earn rewards!

Have you used Pepsinogen I Antibody (8003 (99/12)) - BSA Free?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card

Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs

No product specific FAQs exist for this product.

View all FAQs for Antibodies