Periaxin Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-89598

Novus Biologicals
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Cited:

Canine

Applications

Validated:

Immunohistochemistry-Paraffin

Cited:

Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, IF/IHC

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all Periaxin Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: MKVPDMKLPEIKLPKVPEMAVPDVHLPEVQLPKVSEIRLPEMQVPKVPDVHLPKAPEVKLPRAPEVQLKATKAEQAEGMEFGFKMPKMTMPKLGRAESPSRGKPGEAGAEVSGKLVTLPCLQPEVDGEAHVGVPSLTLPSVELDL

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Periaxin Antibody - BSA Free

Periaxin Antibody - BSA Free Immunohistochemistry-Paraffin: Periaxin Antibody - BSA Free [NBP1-89598]

Immunohistochemistry-Paraffin: Periaxin Antibody - BSA Free [NBP1-89598]

Analysis in human lung and liver tissues using NBP1-89598 antibody. Corresponding PRX RNA-seq data are presented for the same tissues.
Periaxin Antibody - BSA Free Immunohistochemistry-Paraffin: Periaxin Antibody - BSA Free [NBP1-89598]

Immunohistochemistry-Paraffin: Periaxin Antibody - BSA Free [NBP1-89598]

Analysis in human lung and liver tissues. Corresponding RNA-seq data are presented for the same tissues.
Periaxin Antibody - BSA Free Immunohistochemistry-Paraffin: Periaxin Antibody - BSA Free [NBP1-89598]

Immunohistochemistry-Paraffin: Periaxin Antibody - BSA Free [NBP1-89598]

Staining of human testis shows no positivity in cells in seminiferous ducts as expected.
Periaxin Antibody - BSA Free Immunohistochemistry-Paraffin: Periaxin Antibody - BSA Free [NBP1-89598]

Immunohistochemistry-Paraffin: Periaxin Antibody - BSA Free [NBP1-89598]

Staining of human kidney shows strong membranous positivity in cells in glomeruli.
Periaxin Antibody - BSA Free Immunohistochemistry-Paraffin: Periaxin Antibody - BSA Free [NBP1-89598]

Immunohistochemistry-Paraffin: Periaxin Antibody - BSA Free [NBP1-89598]

Staining of human liver shows no positivity in hepatocytes as expected.
Periaxin Antibody - BSA Free Immunohistochemistry-Paraffin: Periaxin Antibody - BSA Free [NBP1-89598]

Immunohistochemistry-Paraffin: Periaxin Antibody - BSA Free [NBP1-89598]

Staining of human lung shows strong membranous positivity in pneumocytes.

Applications for Periaxin Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:1000 - 1:2500
Application Notes
IHC-Paraffin, HIER pH 6 retrieval is recommended.

Reviewed Applications

Read 1 review rated 5 using NBP1-89598 in the following applications:

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Periaxin

Periaxin is involved in peripheral nerve myelin upkeep. The encoded protein contains 2 PDZ domains which were named after PSD95 (post synaptic density protein), DlgA (Drosophila disc large tumor suppressor), and ZO1 (a mammalian tight junction protein). Two alternatively spliced transcript variants have been described for this gene which encode different protein isoforms and which are targeted differently in the Schwann cell. Mutations in this gene cause Charcot-Marie-Tooth neuoropathy, type 4F and Dejerine-Sottas neuropathy. [provided by RefSeq, Jul 2008]

Alternate Names

CMT4F, PRX

Gene Symbol

PRX

Additional Periaxin Products

Product Documents for Periaxin Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for Periaxin Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for Periaxin Antibody - BSA Free

Customer Reviews for Periaxin Antibody - BSA Free (1)

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Customer Images

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  • Name: Markus Tammia
    Application: Immunohistochemistry-Frozen
    Sample Tested: Mouse sciatic nerve
    Species: Mouse
    Verified Customer | Posted 07/13/2015
    Mouse sciatic nerve stained with periaxin (green) and DAPI (blue)
    Periaxin Antibody - BSA Free NBP1-89598

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Protocols

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FAQs for Periaxin Antibody - BSA Free

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  • Q: Could you tell me if you expect the periaxin antibody NBP1-89598 to react with rat tissue?

    A: This antibody has not been tested in rat. I performed a blast homology comparison to Rat with the immunogen and found only a 69% homology. However this has been validated in Mouse and Mouse only has a 72% homology and it seems to work fine. Mouse and rat are 92% homologous. The problem is that we cannot guarantee the antibody will work in rat but we can presume it will. This antibody was developed against Recombinant Protein corresponding to amino acids: MKVPDMKLPEIKLPKVPEMAVPDVHLPEVQLPKVSEIRLPEMQVPKVPDVHLPKAPEVKLPRAPEVQLKATKAEQAEGMEFGFKMPKMTMPKLGRAESPSRGKPGEAGAEVSGKLVTLPCLQPEVDGEAHVGVPSLTLPSVELDL

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