SFRS8 Antibody

Name: SFRS8 Antibody
Brand: Novus Biologicals
SKU: NB100-55245
Price: 459 USD
Availability: InStock

Novus Biologicals | Catalog # NB100-55245

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Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

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Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 500 and 550 of human splicing factor, arginine/serine-rich 8 using the numbering given in entry NP_004583.2 (GeneID 6433).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SFRS8 Antibody

Western Blot: SFRS8 Antibody [NB100-55245]

Western Blot: SFRS8 Antibody [NB100-55245] - Whole cell lysate (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded) from HeLa cells. Affinity purified rabbit anti-SFRS8/SWAP antibody NB100-55245 used for WB at 0.04 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate (B).

Immunohistochemistry: SFRS8 Antibody [NB100-55245]

Immunohistochemistry: SFRS8 Antibody [NB100-55245] - Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti- SFRS8/SWAP used at a dilution of 1:200 (1ug/ml). Detection: DAB

Immunohistochemistry-Paraffin: SFRS8 Antibody [NB100-55245]

Immunohistochemistry-Paraffin: SFRS8 Antibody [NB100-55245] - FFPE section of human lung carcinoma. Affinity purified rabbit anti-SFRS8/SWAP used at a dilution of 1:100.

Applications for SFRS8 Antibody

Application

Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Immunoprecipitation

2-5 ug/mg lysate

Western Blot

1:2000-1:10000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

TBS and 0.1% BSA

Preservative

0.09% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: SFRS8

SFRS8 regulates the splicing of CD45, a protein which through alternative splice variants, has an essential role in activating T cells. T cells are involved in the pathogenesis of atopic diseases such as asthma, making SFRS8 a very interesting candidate gene in the region. SFRS8 could act as a weak predisposing gene for asthma. The basic functions of SFRS8 are the mediation of protein-protein interactions within the intron during spliceosome assembly, independently binding to exonic enhancer sequences, and recruiting components to adjacent introns for splice-site recognition and alternative splicing.

Alternate Names

Drosophila homolog), Drosophila), SFRS8, Splicing factor, arginine/serine-rich 8, splicing factor, arginine/serine-rich 8 (suppressor-of-white-apricot, splicing factor, arginine/serine-rich 8 (suppressor-of-white-apricot homolog, splicing factor, suppressor of white-apricot homolog, splicing factor, suppressor of white-apricot homolog (Drosophila), Suppressor of white apricot protein homolog, SWAPMGC167082

Entrez Gene IDs

6433 (Human)

Gene Symbol

SFSWAP

UniProt

NP_004583.2 (Human)

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Product Specific Notices for SFRS8 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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