SLC4A11 Antibody

Novus Biologicals | Catalog # NBP1-46156

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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (100%), Canine (100%), Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
View all SLC4A11 Primary Antibodies »

Product Specifications

Immunogen

This SLC4A11 Antibody was developed against a peptide with sequence C-HTSRKYLKLKNFKEE corresponding to internal region according to NP_114423.1.

Epitope

internal region

Reactivity Notes

Porcine reactivity reported from a verified customer review.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for SLC4A11 Antibody

Western Blot: SLC4A11 Antibody [NBP1-46156]

Western Blot: SLC4A11 Antibody [NBP1-46156]

Western Blot: SLC4A11 Antibody [NBP1-46156] - Porcine kidney tissue lysates. Lane 1 - 15 ug. Lane 2 - 30 ug. Lane 3 - 60 ug. Antibody at 1:500. Secondary antibody at 1:1000. Western blot image submitted by a verified customer review.
Immunohistochemistry-Paraffin: SLC4A11 Antibody [NBP1-46156]

Immunohistochemistry-Paraffin: SLC4A11 Antibody [NBP1-46156]

Immunohistochemistry-Paraffin: SLC4A11 Antibody [NBP1-46156] - Staining of paraffin embedded Human Kidney. Antibody at 3.75 ug/mL. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
Western Blot: SLC4A11 Antibody [NBP1-46156]

Western Blot: SLC4A11 Antibody [NBP1-46156]

Western Blot: SLC4A11 Antibody [NBP1-46156] - Staining of Human Kidney lysate (35 ug protein in RIPA buffer). Antibody at 0.3 ug/mL. Primary incubation was 1 hour. Detected by chemiluminescence. Approx 90 kDa band observed in Human Kidney lysates (calculated MW of 99.6 kDa according to NP_114423.1). An additional band of unknown identity was also consistently observed at 26 kDa. This band was successfully blocked by incubation with the immunizing peptide.
SLC4A11 Antibody

Immunohistochemistry: SLC4A11 Antibody [NBP1-46156] -

SLC4A11 is linked to ovarian cancer. (a) Fifty-two genes whose expression was elevated in ovarian cancer tissue compared with healthy tissue are displayed in a Venn diagram. Data were obtained from the GSE40505, GSE18520, GSE66057, TCGA and GTEx datasets. (b) SLC4A11 mRNA expression levels in 88 nontumor tissues and 426 OV tissues from the GEPIA database. (c) SLC4A11 expression is used to predict the overall prognosis of ovarian cancer patients. Data obtained from GEPIA. (d) The degree of SLC4A11 expression in the GEO database (GSE40595, 63 OV, and 14 nontumor tissue samples; GSE18520, 53 OV and 10 nontumor tissue samples; GSE66957, 57 OV and 13 nontumor tissue samples). Chi-square test: *p < 0.05, **p < 0.01, ***p < 0.001. (e) SLC4A11 expression in OV tissue microarrays at various disease stages and in normal tissues. Scale bar: 50 uM. (f) The number of samples expressing SLC4A11 in OV samples (n = 117) and normal tissue samples (n = 16) was determined by blinded IHC. Scoring is based on staining intensity: negative (no positive colouration): 0 points; weak positive (light yellow): 1 point; positive (brownish yellow): 2 points; and strong positive (tan): 3 points. A score greater than 1 is considered high. Image collected and cropped by CiteAb from the following open publication (https://pubmed.ncbi.nlm.nih.gov/40721447), licensed under a CC-BY license. Not internally tested by Novus Biologicals.

Applications for SLC4A11 Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

3.75 ug/mL

Peptide ELISA

Detection limit 1:32000

Western Blot

0.3 - 1 ug/mL

Reviewed Applications

Read 1 review rated 4 using NBP1-46156 in the following applications:

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: SLC4A11

Transporter involved in borate homeostasis. In the absence of borate, it functions as a Na(+) and OH(-)(H(+))channel. In the presence of borate functions as an electrogenic Na(+) coupled borate cotransporter

Alternate Names

Bicarbonate transporter-related protein 1, BTR1bicarbonate transporter related protein 1, CDPD, CHED2, corneal endothelial dystrophy 2 (autosomal recessive), dJ794I6.2, FECD4, MGC126418, MGC126419, NABC1, sodium bicarbonate transporter-like protein 11, Sodium borate cotransporter 1, sodium-coupled borate cotransporter 1, Solute carrier family 4 member 11, solute carrier family 4, sodium bicarbonate transporter-like, member 11, solute carrier family 4, sodium borate transporter, member 11

Entrez Gene IDs

83959 (Human); 269356 (Mouse); 311423 (Rat)

Gene Symbol

SLC4A11

UniProt

NP_114423.1 (Human)

Additional SLC4A11 Products

Product Documents for SLC4A11 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for SLC4A11 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for SLC4A11 Antibody

Customer Reviews for SLC4A11 Antibody (1)

4 out of 5
1 Customer Rating
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4 Stars
100%
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Customer Images

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  • SLC4A11 Antibody
    Name: Kwangwon son
    Application: Western Blot
    Sample Tested: Kidney tissue
    Species: Pig
    Verified Customer | Posted 02/15/2021
    SLC4A11 antibody Validation
    lane 1 - 15ug lane 2 - 30ug lane 3 - 60ug Primary Antibody - 1:1500 Secondary Antibody - 1:1000 5% Blocking Solution
    SLC4A11 Antibody NBP1-46156
    Bio-Techne Response
    This review was submitted through the legacy Novus Innovators Program, reflecting a new species or application tested on a primary antibody.

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